N2a cell

N2a (Neuro-2a) is a fast-growing mouse neuroblastoma cell line. It is possible to differentiate N2a cells into cells that have many properties of neurons, including neurofilaments. N2a cells have been used to study neurotoxicity,[1] Alzheimer's disease,[2] and asymmetric division of mammalian cell lines.[3]

References

  1. ↑ LePage KT, Dickey RW, Gerwick WH, Jester EL, Murray TF (2005). "On the use of neuro-2a neuroblastoma cells versus intact neurons in primary culture for neurotoxicity studies". CRITICAL REVIEWS IN NEUROBIOLOGY 17 (1): 27–50. PMID 16307526.
  2. ↑ Provost P (2010). "Interpretation and applicability of microRNA data to the context of Alzheimer's and age-related diseases". Aging 2 (3): 166–169. PMC 871245. PMID 20375468.
  3. ↑ Ogrodnik M, Salmonowicz H, Brown R, Turkowska J, Sredniawa W, Pattabiraman S, Amen T, Abraham AC, Eichler N, Lyakhovetsky R, Kaganovich D (2014). "Dynamic JUNQ inclusion bodies are asymmetrically inherited in mammalian cell lines through the asymmetric partitioning of vimentin". Proceedings of the National Academy of Sciences of the United States of America 111 (22): 8049–54. doi:10.1073/pnas.1324035111. PMC 4050583. PMID 24843142.

External links


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