NHLH1

Nescient helix loop helix 1
Identifiers
Symbols NHLH1 ; HEN1; NSCL; NSCL1; bHLHa35
External IDs OMIM: 162360 MGI: 98481 HomoloGene: 4089 GeneCards: NHLH1 Gene
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez 4807 18071
Ensembl ENSG00000171786 ENSMUSG00000051251
UniProt Q02575 Q02576
RefSeq (mRNA) NM_005598 NM_010916
RefSeq (protein) NP_005589 NP_035046
Location (UCSC) Chr 1:
160.37 – 160.37 Mb
Chr 1:
172.05 – 172.06 Mb
PubMed search

Helix-loop-helix protein 1 is a protein that in humans is encoded by the NHLH1 gene.[1]

The helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080), LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040).[supplied by OMIM][1]

References

Further reading

This article is issued from Wikipedia - version of the Monday, July 27, 2015. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.