ODZ2

Teneurin transmembrane protein 2
Identifiers
Symbols	TENM2 ; ODZ2; TEN-M2; TNM2
External IDs	OMIM: 610119 MGI: 1345184 HomoloGene: 22672 GeneCards: TENM2 Gene
Gene ontology Molecular function • receptor binding • protein binding • protein homodimerization activity • protein heterodimerization activity • cell adhesion molecule binding Cellular component • intracellular • nucleus • endoplasmic reticulum • Golgi apparatus • plasma membrane • integral component of plasma membrane • cell-cell junction • PML body • cell junction • filopodium • dendrite • growth cone • neuron projection • dendritic spine • synapse • postsynaptic membrane Biological process • negative regulation of transcription from RNA polymerase II promoter • transcription, DNA-templated • heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules • signal transduction • axon guidance • single organismal cell-cell adhesion • calcium-mediated signaling using intracellular calcium source • positive regulation of filopodium assembly • self proteolysis Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	57451	23964
Ensembl	ENSG00000145934	ENSMUSG00000049336
UniProt	Q9NT68	Q9WTS5
RefSeq (mRNA)	NM_001080428	NM_001290702
RefSeq (protein)	NP_001116151	NP_001277631
Location (UCSC)	Chr 5: 167.28 – 168.26 Mb	Chr 11: 36.01 – 37.24 Mb
PubMed search

Teneurin-2 is a protein that in humans is encoded by the ODZ2 gene.^[1][2] This protein belongs to a family of similar teneurins.

References

1. Ben-Zur T, Feige E, Motro B, Wides R (Feb 2000). "The mammalian Odz gene family: homologs of a Drosophila pair-rule gene with expression implying distinct yet overlapping developmental roles". Dev Biol 217 (1): 107–20. doi:10.1006/dbio.1999.9532. PMID 10625539.
2. "Entrez Gene: ODZ2 odz, odd Oz/ten-m homolog 2 (Drosophila)".

Further reading

• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
• Schmutz J, Martin J, Terry A, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 5.". Nature 431 (7006): 268–74. doi:10.1038/nature02919. PMID 15372022.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Bagutti C, Forro G, Ferralli J, et al. (2004). "The intracellular domain of teneurin-2 has a nuclear function and represses zic-1-mediated transcription.". J. Cell. Sci. 116 (Pt 14): 2957–66. doi:10.1242/jcs.00603. PMID 12783990.
• Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. doi:10.1073/pnas.97.7.3491. PMC 16267. PMID 10737800.
• Hirosawa M, Nagase T, Ishikawa K, et al. (2000). "Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain". DNA Res. 6 (5): 329–36. doi:10.1093/dnares/6.5.329. PMID 10574461.
• Oohashi T, Zhou XH, Feng K, et al. (1999). "Mouse Ten-m/Odz Is a New Family of Dimeric Type II Transmembrane Proteins Expressed in Many Tissues". J. Cell Biol. 145 (3): 563–77. doi:10.1083/jcb.145.3.563. PMC 2185078. PMID 10225957.