Omega-hydroxypalmitate O-feruloyl transferase

Omega-hydroxypalmitate O-feruloyl transferase (EC 2.3.1.188, hydroxycinnamoyl-CoA omega-hydroxypalmitic acid O-hydroxycinnamoyltransferase, HHT) is an enzyme with systematic name feruloyl-CoA:16-hydroxypalmitate feruloyltransferase.^[1]^[2]^[3] This enzyme catalyses the following chemical reaction

feruloyl-CoA + 16-hydroxypalmitate

\rightleftharpoons

CoA + 16-feruloyloxypalmitate

p-Coumaroyl-CoA and sinapoyl-CoA also act as substrates.

References

↑ Lotfy, S., Negrel, J. and Javelle, F. (1994). "Formation of feruloyloxypalmitic acid by an enzyme from wound-healing potato tuber discs". Phytochemistry 35: 1419–1424. doi:10.1016/s0031-9422(00)86867-3.
↑ Lotfy, S. Javelle, F. and Negrel, J. (1995). "Distribution of hydroxycinnamoyl-CoA ω-hydroxypalmitic acid O-hydroxycinnamoyltransferase in higher plants". Phytochemistry 40: 389–391. doi:10.1016/0031-9422(95)00284-e.
↑ Lotfy, S. Javelle, F. and Negrel, J. (1996). "Purification and characterization of hydroxycinnamoyl-CoA ω-hydroxypalmitic acid O-hydroxycinnamoyltransferase from tobacco (Nicotiana tabacum L.) cell-suspension cultures". Planta 199: 475–480. doi:10.1007/bf00195742.

External links

Omega-hydroxypalmitate O-feruloyl transferase at the US National Library of Medicine Medical Subject Headings (MeSH)

Transferases: acyltransferases (EC 2.3)

2.3.1: other than amino-acyl groups	acetyltransferases: Acetyl-Coenzyme A acetyltransferase N-Acetylglutamate synthase Choline acetyltransferase Dihydrolipoyl transacetylase Acetyl-CoA C-acyltransferase Beta-galactoside transacetylase Chloramphenicol acetyltransferase N-acetyltransferase Serotonin N-acetyl transferase HGSNAT ARD1A Histone acetyltransferase P300/CBP NAT2 palmitoyltransferases: Carnitine O-palmitoyltransferase CPT1 CPT2 Serine C-palmitoyltransferase SPTLC1 SPTLC2 other: Acyltransferase like 2 Aminolevulinic acid synthase Beta-ketoacyl-ACP synthase Glyceronephosphate O-acyltransferase Lecithin—cholesterol acyltransferase Glycerol-3-phosphate O-acyltransferase 1-acylglycerol-3-phosphate O-acyltransferase 2-acylglycerol-3-phosphate O-acyltransferase ABHD5

2.3.2: Aminoacyltransferases	Gamma-glutamyl transpeptidase Peptidyl transferase Transglutaminase Tissue transglutaminase Keratinocyte transglutaminase Factor XIII

2.3.3: converted into alkyl on transfer	Citrate synthase ATP citrate lyase HMG-CoA synthase Malate synthase

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases(list) EC2 Transferases(list) EC3 Hydrolases(list) EC4 Lyases(list) EC5 Isomerases(list) EC6 Ligases(list)

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