Oxepin-CoA hydrolase

Oxepin-CoA hydrolase
Identifiers
EC number	3.7.1.16
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Oxepin-CoA hydrolase (EC 3.7.1.16, paaZ (gene)) is an enzyme with systematic name 2-oxepin-2(3H)-ylideneacetyl-CoA hydrolyase.^[1][2][3][4] This enzyme catalyses the following chemical reaction

2-oxepin-2(3H)-ylideneacetyl-CoA + H₂O $\rightleftharpoons$ 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde

The enzyme is present in bacteria Escherichia coli.

References

1. Ferrandez, A., Minambres, B., Garcia, B., Olivera, E.R., Luengo, J.M., Garcia, J.L. and Diaz, E. (1998). "Catabolism of phenylacetic acid in Escherichia coli. Characterization of a new aerobic hybrid pathway". J. Biol. Chem. 273 (40): 25974–25986. doi:10.1074/jbc.273.40.25974. PMID 9748275.
2. Park, S.J. and Lee, S.Y. (2003). "Identification and characterization of a new enoyl coenzyme A hydratase involved in biosynthesis of medium-chain-length polyhydroxyalkanoates in recombinant Escherichia coli". J. Bacteriol. 185 (18): 5391–5397. doi:10.1128/jb.185.18.5391-5397.2003. PMID 12949091.
3. Ismail, W., El-Said Mohamed, M., Wanner, B.L., Datsenko, K.A., Eisenreich, W., Rohdich, F., Bacher, A. and Fuchs, G. (2003). "Functional genomics by NMR spectroscopy. Phenylacetate catabolism in Escherichia coli". Eur. J. Biochem. 270 (14): 3047–3054. doi:10.1046/j.1432-1033.2003.03683.x. PMID 12846838.
4. Teufel, R., Mascaraque, V., Ismail, W., Voss, M., Perera, J., Eisenreich, W., Haehnel, W. and Fuchs, G. (2010). "Bacterial phenylalanine and phenylacetate catabolic pathway revealed". Proc. Natl. Acad. Sci. USA 107: 14390–14395. doi:10.1073/pnas.1005399107. PMC 2922514. PMID 20660314.

External links

• Oxepin-CoA hydrolase at the US National Library of Medicine Medical Subject Headings (MeSH)