Oxygenation index

The oxygenation index is a calculation used in intensive care medicine to measure the fraction of inspired oxygen (FiO2) and its usage within the body.

A lower oxygenation index is better - this can be inferred by the equation itself. As the oxygenation of a person improves, they will be able to achieve a higher PaO2 at a lower FiO2. This would be reflected on the formula as a decrease in the numerator or an increase in the denominator - thus lowering the OI. Typically an OI threshold is set for when a neonate should be placed on ECMO, for example >40.

Equation

OI = \frac{FiO_2 \times M_\text{PAW}}{PaO_2}

^[1]

$FiO_2$ : Fraction of inspired oxygen, in percent;
$M_\text{PAW}$ : Mean airway pressure, in mmHg;
$PaO_2$ : Partial pressure of oxygen in arterial blood, in mmHg.

References

↑ Ortiz RM, Cilley RE, Bartlett RH. Extracorporeal membrane oxygenation in pediatric respiratory failure. Pediatr Clin North Am. 1987 Feb;34(1):39-46.

Mechanical ventilation

Fundamentals	Modes of mechanical ventilation Mechanical ventilation in emergencies Mechanical ventilation in neonates Nomenclature of mechanical ventilation

Modes	IMV/SIMV CMV ACV CSV PAP BPAP CPAP APRV MMV PAV ASV HFV

Related illness	ARDS Pulmonary barotrauma Pulmonary volutrauma Ventilator-associated pneumonia Oxygen toxicity Ventilator-associated lung injury

Pressure	P_EEP FiO₂ Δ_P P_IP P_S P_AW P_plat

Volumes	V_T V_E V_f

Other	C_dyn C_static P_AO₂ V_D/V_T OI A-a gradient

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