PAAF1

Proteasomal ATPase-associated factor 1
Identifiers
Symbols PAAF1 ; PAAF; Rpn14; WDR71
External IDs HomoloGene: 49821 GeneCards: PAAF1 Gene
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez 80227 n/a
Ensembl ENSG00000175575 n/a
UniProt Q9BRP4 n/a
RefSeq (mRNA) NM_001267803 n/a
RefSeq (protein) NP_001254732 n/a
Location (UCSC) Chr 11:
73.88 – 73.93 Mb
n/a
PubMed search n/a

Proteasomal ATPase-associated factor 1 is an enzyme that in humans is encoded by the PAAF1 gene.[1][2][3][4]

Interactions

PAAF1 has been shown to interact with PSMD10.[5]

References

  1. Park Y, Hwang YP, Lee JS, Seo SH, Yoon SK, Yoon JB (May 2005). "Proteasomal ATPase-associated factor 1 negatively regulates proteasome activity by interacting with proteasomal ATPases". Molecular and Cellular Biology 25 (9): 3842–53. doi:10.1128/MCB.25.9.3842-3853.2005. PMC 1084299. PMID 15831487.
  2. Ponnappan S, Ovaa H, Ponnappan U (Mar 2007). "Lower expression of catalytic and structural subunits of the proteasome contributes to decreased proteolysis in peripheral blood T lymphocytes during aging". The International Journal of Biochemistry & Cell Biology 39 (4): 799–809. doi:10.1016/j.biocel.2007.01.002. PMID 17317272.
  3. Lassot I, Latreille D, Rousset E, Sourisseau M, Linares LK, Chable-Bessia C, Coux O, Benkirane M, Kiernan RE (Feb 2007). "The proteasome regulates HIV-1 transcription by both proteolytic and nonproteolytic mechanisms". Molecular Cell 25 (3): 369–83. doi:10.1016/j.molcel.2006.12.020. PMID 17289585.
  4. "Entrez Gene: WDR71 WD repeat domain 71".
  5. Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Molecular Systems Biology 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.

Further reading

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