PAM16

Presequence translocase-associated motor 16 homolog (S. cerevisiae)
Identifiers
Symbols	PAM16 ; CGI-136; MAGMAS; TIM16; TIMM16
External IDs	OMIM: 614336 HomoloGene: 41100 GeneCards: PAM16 Gene
Gene ontology Molecular function • protein binding Cellular component • presequence translocase-associated import motor • mitochondrial inner membrane presequence translocase complex • mitochondrial matrix • extrinsic component of mitochondrial inner membrane • protein complex Biological process • protein targeting to mitochondrion • protein import into mitochondrial matrix • protein import into mitochondrial matrix • negative regulation of ATPase activity • cellular protein metabolic process Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	51025	66449
Ensembl	ENSG00000217930	ENSMUSG00000014301
UniProt	Q9Y3D7	Q9CQV1
RefSeq (mRNA)	NM_016069	NM_025571
RefSeq (protein)	NP_057153	NP_079847
Location (UCSC)	Chr 16: 4.33 – 4.36 Mb	Chr 16: 4.62 – 4.62 Mb
PubMed search

Mitochondrial import inner membrane translocase subunit TIM16 also known as presequence translocated-associated motor subunit PAM16 is a protein that in humans is encoded by the PAM16 gene.^[1]

References

1. "Entrez Gene: Presequence translocase-associated motor 16 homolog (S. cerevisiae)".

Further reading

• Tagliati F, Gentilin E, Buratto M, Molè D, degli Uberti EC, Zatelli MC (Oct 2010). "Magmas, a gene newly identified as overexpressed in human and mouse ACTH-secreting pituitary adenomas, protects pituitary cells from apoptotic stimuli". Endocrinology 151 (10). doi:10.1210/en.2010-0441. PMID 20719856.
• Sinha D, Joshi N, Chittoor B, Samji P, D'Silva P (Apr 2010). "Role of Magmas in protein transport and human mitochondria biogenesis". Human Molecular Genetics 19 (7). doi:10.1093/hmg/ddq002. PMID 20053669.
• Jubinsky PT, Short MK, Mutema G, Morris RE, Ciraolo GM, Li M (Feb 2005). "Magmas expression in neoplastic human prostate". Journal of Molecular Histology 36 (1-2). doi:10.1007/s10735-004-3840-8. PMID 15704001.
• Jubinsky PT, Messer A, Bender J, Morris RE, Ciraolo GM, Witte DP, Hawley RG, Short MK (Dec 2001). "Identification and characterization of Magmas, a novel mitochondria-associated protein involved in granulocyte-macrophage colony-stimulating factor signal transduction". Experimental Hematology 29 (12). PMID 11750097.