PAPLN

Papilin, proteoglycan-like sulfated glycoprotein
Identifiers
Symbols	PAPLN ; DKFZp434F053; MGC50452
External IDs	MGI: 2386139 HomoloGene: 71541 GeneCards: PAPLN Gene
Gene ontology Molecular function • metalloendopeptidase activity • serine-type endopeptidase inhibitor activity • zinc ion binding Cellular component • basement membrane Biological process • proteolysis • negative regulation of endopeptidase activity Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	89932	170721
Ensembl	ENSG00000100767	ENSMUSG00000021223
UniProt	O95428	Q9EPX2
RefSeq (mRNA)	NM_173462	NM_001205343
RefSeq (protein)	NP_775733	NP_001192272
Location (UCSC)	Chr 14: 73.24 – 73.27 Mb	Chr 12: 83.76 – 83.79 Mb
PubMed search

Papilin is a protein that in humans is encoded by the PAPLN gene.^[1][2][3] Papilin is an extracellular matrix glycoprotein.

References

1. "Entrez Gene: papilin".
2. Kramerova IA, Kawaguchi N, Fessler LI, Nelson RE, Chen Y, Kramerov AA, Kusche-Gullberg M, Kramer JM, Ackley BD, Sieron AL, Prockop DJ, Fessler JH (December 2000). "Papilin in development; a pericellular protein with a homology to the ADAMTS metalloproteinases". Development 127 (24): 5475–85. PMID 11076767.
3. Apte SS (November 2009). "A disintegrin-like and metalloprotease (reprolysin-type) with thrombospondin type 1 motif (ADAMTS) superfamily: functions and mechanisms". J. Biol. Chem. 284 (46): 31493–7. doi:10.1074/jbc.R109.052340. PMC 2797218. PMID 19734141.

Further reading

• Rose JE, Behm FM, Drgon T, et al. (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
• Laje G, Allen AS, Akula N, et al. (2009). "Genome-wide association study of suicidal ideation emerging during citalopram treatment of depressed outpatients". Pharmacogenet. Genomics 19 (9): 666–74. doi:10.1097/FPC.0b013e32832e4bcd. PMC 2819190. PMID 19724244.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.