PDE6C
| Phosphodiesterase 6C, cGMP-specific, cone, alpha prime | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | PDE6C ; ACHM5; COD4; PDEA2 | ||||||||||||
| External IDs | OMIM: 600827 MGI: 105956 HomoloGene: 4521 ChEMBL: 3977 GeneCards: PDE6C Gene | ||||||||||||
| EC number | 3.1.4.35 | ||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 5146 | 110855 | |||||||||||
| Ensembl | ENSG00000095464 | ENSMUSG00000024992 | |||||||||||
| UniProt | P51160 | Q91ZQ1 | |||||||||||
| RefSeq (mRNA) | NM_006204 | NM_001170959 | |||||||||||
| RefSeq (protein) | NP_006195 | NP_001164430 | |||||||||||
| Location (UCSC) |
Chr 10: 93.61 – 93.67 Mb |
Chr 19: 38.13 – 38.18 Mb | |||||||||||
| PubMed search | |||||||||||||
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' is an enzyme that in humans is encoded by the PDE6C gene.[1]
References
Further reading
- Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature 429 (6990): 375–81. doi:10.1038/nature02462. PMID 15164054.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Bertazolli-Filho R, Ghosh S, Huang W, et al. (2001). "Molecular evidence that human ocular ciliary epithelium expresses components involved in phototransduction". Biochem. Biophys. Res. Commun. 284 (2): 317–25. doi:10.1006/bbrc.2001.4970. PMID 11394879.
- Harrington JJ, Sherf B, Rundlett S, et al. (2001). "Creation of genome-wide protein expression libraries using random activation of gene expression". Nat. Biotechnol. 19 (5): 440–5. doi:10.1038/88107. PMID 11329013.
- Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
- Gao YQ, Danciger M, Longmuir R, et al. (1999). "Screening of the gene encoding the alpha'-subunit of cone cGMP-PDE in patients with retinal degenerations". Invest. Ophthalmol. Vis. Sci. 40 (8): 1818–22. PMID 10393054.
- Feshchenko EA, Andreeva SG, Suslova VA, et al. (1996). "Human cone-specific cGMP phosphodiesterase alpha' subunit: complete cDNA sequence and gene arrangement". FEBS Lett. 381 (1–2): 149–52. doi:10.1016/0014-5793(96)00104-4. PMID 8641425.
- Viczian AS, Piriev NI, Farber DB (1996). "Isolation and characterization of a cDNA encoding the alpha' subunit of human cone cGMP-phosphodiesterase". Gene 166 (2): 205–11. doi:10.1016/0378-1119(95)00585-4. PMID 8543163.
- Piriev NI, Viczian AS, Ye J, et al. (1996). "Gene structure and amino acid sequence of the human cone photoreceptor cGMP-phosphodiesterase alpha' subunit (PDEA2) and its chromosomal localization to 10q24". Genomics 28 (3): 429–35. doi:10.1006/geno.1995.1171. PMID 7490077.
External links
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