PDLIM2

PDZ and LIM domain 2 (mystique)
PDB rendering based on 2pa1.
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 2PA1​, 3PDV​
Identifiers
Symbols	PDLIM2 ; MYSTIQUE; SLIM
External IDs	OMIM: 609722 MGI: 2384850 HomoloGene: 11006 GeneCards: PDLIM2 Gene
Gene ontology Molecular function • zinc ion binding • filamin binding • myosin heavy chain binding • muscle alpha-actinin binding Cellular component • stress fiber • nucleus • focal adhesion • actin cytoskeleton • cortical actin cytoskeleton • extracellular exosome Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	64236	213019
Ensembl	ENSG00000120913	ENSMUSG00000022090
UniProt	Q96JY6	Q8R1G6
RefSeq (mRNA)	NM_021630	NM_001253736
RefSeq (protein)	NP_067643	NP_001240665
Location (UCSC)	Chr 8: 22.58 – 22.6 Mb	Chr 14: 70.16 – 70.18 Mb
PubMed search

PDZ and LIM domain protein 2 is a protein that in humans is encoded by the PDLIM2 gene.^[1]

References

1. "Entrez Gene: PDLIM2 PDZ and LIM domain 2 (mystique)".

Further reading

• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
• Hattori A, Okumura K, Nagase T, et al. (2001). "Characterization of long cDNA clones from human adult spleen". DNA Res. 7 (6): 357–66. doi:10.1093/dnares/7.6.357. PMID 11214971.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Shin BK, Wang H, Yim AM, et al. (2003). "Global profiling of the cell surface proteome of cancer cells uncovers an abundance of proteins with chaperone function". J. Biol. Chem. 278 (9): 7607–16. doi:10.1074/jbc.M210455200. PMID 12493773.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Wan D, Gong Y, Qin W, et al. (2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression". Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15724–9. doi:10.1073/pnas.0404089101. PMC 524842. PMID 15498874.
• Loughran G, Healy NC, Kiely PA, et al. (2005). "Mystique Is a New Insulin-like Growth Factor-I-regulated PDZ-LIM Domain Protein That Promotes Cell Attachment and Migration and Suppresses Anchorage-independent Growth". Mol. Biol. Cell 16 (4): 1811–22. doi:10.1091/mbc.E04-12-1052. PMC 1073663. PMID 15659642.
• Tanaka T, Grusby MJ, Kaisho T (2007). "PDLIM2-mediated termination of transcription factor NF-kappaB activation by intranuclear sequestration and degradation of the p65 subunit". Nat. Immunol. 8 (6): 584–91. doi:10.1038/ni1464. PMID 17468759.