PDZRN3

PDZ domain containing ring finger 3
PDB rendering based on 1uhp.
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 1UHP​, 1WH1​
Identifiers
Symbols	PDZRN3 ; LNX3; SEMACAP3; SEMCAP3
External IDs	OMIM: 609729 MGI: 1933157 HomoloGene: 10328 GeneCards: PDZRN3 Gene
Gene ontology Molecular function • ubiquitin-protein transferase activity • zinc ion binding • ligase activity • ubiquitin protein ligase activity Cellular component • neuromuscular junction Biological process • neuromuscular junction development • protein ubiquitination Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	23024	55983
Ensembl	ENSG00000121440	ENSMUSG00000035357
UniProt	Q9UPQ7	Q69ZS0
RefSeq (mRNA)	NM_001303139	NM_018884
RefSeq (protein)	NP_001290068	NP_061372
Location (UCSC)	Chr 3: 73.38 – 73.62 Mb	Chr 6: 101.15 – 101.38 Mb
PubMed search

PDZ domain-containing RING finger protein 3 is a protein that in humans is encoded by the PDZRN3 gene.^[1][2]

References

1. Kikuno R, Nagase T, Ishikawa K, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Oct 1999). "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res 6 (3): 197–205. doi:10.1093/dnares/6.3.197. PMID 10470851.
2. "Entrez Gene: PDZRN3 PDZ domain containing RING finger 3".

Further reading

• Bach I, Rodriguez-Esteban C, Carrière C, et al. (1999). "RLIM inhibits functional activity of LIM homeodomain transcription factors via recruitment of the histone deacetylase complex.". Nat. Genet. 22 (4): 394–9. doi:10.1038/11970. PMID 10431247.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Katoh M, Katoh M (2004). "Identification and characterization of PDZRN3 and PDZRN4 genes in silico.". Int. J. Mol. Med. 13 (4): 607–13. doi:10.3892/ijmm.13.4.607. PMID 15010864.
• Hassel S, Eichner A, Yakymovych M, et al. (2004). "Proteins associated with type II bone morphogenetic protein receptor (BMPR-II) and identified by two-dimensional gel electrophoresis and mass spectrometry.". Proteomics 4 (5): 1346–58. doi:10.1002/pmic.200300770. PMID 15188402.
• Santin AD, Zhan F, Bellone S, et al. (2004). "Gene expression profiles in primary ovarian serous papillary tumors and normal ovarian epithelium: identification of candidate molecular markers for ovarian cancer diagnosis and therapy.". Int. J. Cancer 112 (1): 14–25. doi:10.1002/ijc.20408. PMID 15305371.
• Meyer G, Varoqueaux F, Neeb A, et al. (2005). "The complexity of PDZ domain-mediated interactions at glutamatergic synapses: a case study on neuroligin.". Neuropharmacology 47 (5): 724–33. doi:10.1016/j.neuropharm.2004.06.023. PMID 15458844.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.