PGM2

Phosphoglucomutase 2
Identifiers
Symbols	PGM2 ; MSTP006
External IDs	OMIM: 172000 MGI: 97564 HomoloGene: 6693 GeneCards: PGM2 Gene
EC number	5.4.2.2, 5.4.2.7
Gene ontology Molecular function • magnesium ion binding • phosphoglucomutase activity • protein binding • phosphopentomutase activity Cellular component • cytosol • extracellular exosome Biological process • carbohydrate metabolic process • glycogen biosynthetic process • glycogen catabolic process • glucose metabolic process • galactose catabolic process • small molecule metabolic process • deoxyribose phosphate catabolic process Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	55276	66681
Ensembl	ENSG00000169299	ENSMUSG00000029171
UniProt	Q96G03	Q7TSV4
RefSeq (mRNA)	NM_018290	NM_025700
RefSeq (protein)	NP_060760	NP_079976
Location (UCSC)	Chr 4: 37.83 – 37.86 Mb	Chr 5: 64.09 – 64.13 Mb
PubMed search

Phosphoglucomutase-2 is an enzyme that in humans is encoded by the PGM2 gene.^[1][2]

References

1. Whitehouse DB, Tomkins J, Lovegrove JU, Hopkinson DA, McMillan WO (May 1998). "A phylogenetic approach to the identification of phosphoglucomutase genes". Mol Biol Evol 15 (4): 456–62. doi:10.1093/oxfordjournals.molbev.a025942. PMID 9549096.
2. "Entrez Gene: PGM2 phosphoglucomutase 2".

Further reading

• Sparkes RS, Mohandas T, Sparkes MC, Shulkin JD (1978). "Regional localization of human phosphoglucomutase-2 locus on chromosome 4.". Exp. Cell Res. 111 (2): 492–5. doi:10.1016/0014-4827(78)90200-8. PMID 564278.
• Francke U, Brown S (1979). "Regional assignment of genes for phosphoglucomutase2 and peptidase S to 4pter leads to 4q21 in man.". Cytogenet. Cell Genet. 22 (1–6): 401–5. doi:10.1159/000130982. PMID 752511.
• Sparkes RS, Mohandas T, Sparkes MC, Shulkin JD (1979). "Human PGM2 (E.C. 2.7.5.1) mapped to 4pter leads to 4q25". Cytogenet. Cell Genet. 22 (1–6): 406–7. doi:10.1159/000130983. PMID 752512.
• Wijnen LM, Grzeschik KH, Pearson PL, Meera Khan P (1977). "The human PGM-2 and its chromosomal localization in man-mouse hybrids". Hum. Genet. 37 (3): 271–8. doi:10.1007/BF00393608. PMID 885546.
• McAlpine PJ, Mohandas T, Komarnicki L, et al. (1976). "Further data on the assignment of the phosphoglucomutase2 (PGM2) gene locus to chromosome 4 in man". Cytogenet. Cell Genet. 14 (3–6): 368–9. doi:10.1159/000130386. PMID 1192820.
• McAlpine PJ, Mohandas T, Komarnicki L, et al. (1976). "Further data on the assignment of the phosphoglucomutase (PGM2) gene locus to chromosome 4 in man". Birth Defects Orig. Artic. Ser. 11 (3): 198–9. PMID 1203483.
• Hopkinson DA, Harris H (1966). "Evidence for a second "structural" locus determining human phosphoglucomutase". Nature 208 (5008): 410–2. doi:10.1038/208410a0. PMID 5885461.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Gevaert K, Goethals M, Martens L, et al. (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nat. Biotechnol. 21 (5): 566–9. doi:10.1038/nbt810. PMID 12665801.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Maliekal P, Sokolova T, Vertommen D, et al. (2007). "Molecular identification of mammalian phosphopentomutase and glucose-1,6-bisphosphate synthase, two members of the alpha-D-phosphohexomutase family". J. Biol. Chem. 282 (44): 31844–51. doi:10.1074/jbc.M706818200. PMID 17804405.