PHLDB1

Pleckstrin homology-like domain, family B, member 1
Identifiers
Symbols	PHLDB1 ; LL5A
External IDs	OMIM: 612834 MGI: 2143230 HomoloGene: 15903 GeneCards: PHLDB1 Gene
Gene ontology Molecular function • phospholipid binding Cellular component • basal cortex Biological process • regulation of gastrulation • regulation of epithelial to mesenchymal transition • regulation of microtubule cytoskeleton organization • positive regulation of basement membrane assembly involved in embryonic body morphogenesis Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	23187	102693
Ensembl	ENSG00000019144	ENSMUSG00000048537
UniProt	Q86UU1	Q6PDH0
RefSeq (mRNA)	NM_001144758	NM_153537
RefSeq (protein)	NP_001138230	NP_705765
Location (UCSC)	Chr 11: 118.61 – 118.66 Mb	Chr 9: 44.69 – 44.74 Mb
PubMed search

Pleckstrin homology-like domain family B member 1 is a protein that in humans is encoded by the PHLDB1 gene.^[1][2]

References

1. Katoh M, Katoh M (Oct 2003). "Identification and characterization of human LL5A gene and mouse Ll5a gene in silico". Int J Oncol 23 (5): 1477–83. doi:10.3892/ijo.23.5.1477. PMID 14532993.
2. "Entrez Gene: PHLDB1 pleckstrin homology-like domain, family B, member 1".

Further reading

• Nakajima D, Okazaki N, Yamakawa H, Kikuno R, Ohara O, Nagase T (June 2002). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954.
• Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (June 1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 5 (3): 169–76. doi:10.1093/dnares/5.3.169. PMID 9734811.
• Dowler S, Currie RA, Campbell DG, Deak M, Kular G, Downes CP, Alessi DR (October 2000). "Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities". Biochem. J. 351 (Pt 1): 19–31. doi:10.1042/0264-6021:3510019. PMC 1221362. PMID 11001876.
• Hotta A, Kawakatsu T, Nakatani T, Sato T, Matsui C, Sukezane T, Akagi T, Hamaji T, Grigoriev I, Akhmanova A, Takai Y, Mimori-Kiyosue Y (May 2010). "Laminin-based cell adhesion anchors microtubule plus ends to the epithelial cell basal cortex through LL5alpha/beta". J. Cell Biol. 189 (5): 901–17. doi:10.1083/jcb.200910095. PMC 2878951. PMID 20513769.