PLXNA3

Plexin A3
Identifiers
Symbols	PLXNA3 ; 6.3; HSSEXGENE; PLXN3; PLXN4; XAP-6
External IDs	OMIM: 300022 MGI: 107683 HomoloGene: 7481 GeneCards: PLXNA3 Gene
Gene ontology Molecular function • transmembrane signaling receptor activity • protein binding • semaphorin receptor activity Cellular component • semaphorin receptor complex • plasma membrane • membrane • integral component of membrane Biological process • multicellular organismal development • axon guidance • facial nerve structural organization • trigeminal nerve structural organization • hippocampus development • branchiomotor neuron axon guidance • pyramidal neuron development • negative regulation of axon extension involved in axon guidance • negative chemotaxis • positive regulation of cytoskeleton organization • semaphorin-plexin signaling pathway • semaphorin-plexin signaling pathway involved in axon guidance Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	55558	18846
Ensembl	ENSG00000130827	ENSMUSG00000031398
UniProt	P51805	P70208
RefSeq (mRNA)	NM_017514	NM_008883
RefSeq (protein)	NP_059984	NP_032909
Location (UCSC)	Chr X: 154.46 – 154.48 Mb	Chr X: 74.33 – 74.34 Mb
PubMed search

Plexin-A3 is a protein that in humans is encoded by the PLXNA3 gene.^[1][2][3]

References

1. Bione S, Tamanini F, Maestrini E, Tribioli C, Poustka A, Torri G, Rivella S, Toniolo D (Jan 1994). "Transcriptional organization of a 450-kb region of the human X chromosome in Xq28". Proc Natl Acad Sci U S A 90 (23): 10977–81. doi:10.1073/pnas.90.23.10977. PMC 47904. PMID 8248200.
2. Chen EY, Zollo M, Mazzarella R, Ciccodicola A, Chen CN, Zuo L, Heiner C, Burough F, Repetto M, Schlessinger D, D'Urso M (Jun 1997). "Long-range sequence analysis in Xq28: thirteen known and six candidate genes in 219.4 kb of high GC DNA between the RCP/GCP and G6PD loci". Hum Mol Genet 5 (5): 659–68. doi:10.1093/hmg/5.5.659. PMID 8733135.
3. "Entrez Gene: PLXNA3 plexin A3".

Further reading

• Sedlacek Z, Korn B, Konecki DS, Siebenhaar R, Coy JF, Kioschis P, Poustka A (1994). "Construction of a transcription map of a 300 kb region around the human G6PD locus by direct cDNA selection". Hum. Mol. Genet. 2 (11): 1865–9. doi:10.1093/hmg/2.11.1865. PMID 8281148.
• Maestrini E, Tamagnone L, Longati P, Cremona O, Gulisano M, Bione S, Tamanini F, Neel BG, Toniolo D, Comoglio PM (1996). "A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor". Proc. Natl. Acad. Sci. U.S.A. 93 (2): 674–8. doi:10.1073/pnas.93.2.674. PMC 40111. PMID 8570614.
• Kameyama T, Murakami Y, Suto F, Kawakami A, Takagi S, Hirata T, Fujisawa H (1996). "Identification of plexin family molecules in mice". Biochem. Biophys. Res. Commun. 226 (2): 396–402. doi:10.1006/bbrc.1996.1367. PMID 8806646.
• Tamagnone L, Artigiani S, Chen H, He Z, Ming GI, Song H, Chedotal A, Winberg ML, Goodman CS, Poo M, Tessier-Lavigne M, Comoglio PM (1999). "Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates". Cell 99 (1): 71–80. doi:10.1016/S0092-8674(00)80063-X. PMID 10520995.
• Dias Neto E, Correa RG, Verjovski-Almeida S, Briones MR, Nagai MA, da Silva W, Zago MA, Bordin S, Costa FF, Goldman GH, Carvalho AF, Matsukuma A, Baia GS, Simpson DH, Brunstein A, de Oliveira PS, Bucher P, Jongeneel CV, O'Hare MJ, Soares F, Brentani RR, Reis LF, de Souza SJ, Simpson AJ (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. doi:10.1073/pnas.97.7.3491. PMC 16267. PMID 10737800.
• Brandenberger R, Wei H, Zhang S, Lei S, Murage J, Fisk GJ, Li Y, Xu C, Fang R, Guegler K, Rao MS, Mandalam R, Lebkowski J, Stanton LW (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197.
• Fu GK, Wang JT, Yang J, Au-Young J, Stuve LL (2005). "Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes". Genomics 84 (1): 205–10. doi:10.1016/j.ygeno.2004.01.011. PMID 15203218.