PMEG (antiviral)

PMEG (antiviral)
Names

IUPAC name 2-(2-Amino-6-oxo-3H-purin-9-yl)ethoxymethylphosphonic acid
Other names 9-((2-Phosphonylmethoxy)ethyl)guanine
Identifiers
CAS Number	114088-58-3
Jmol interactive 3D	Image
PubChem	64989
InChI InChI=1S/C8H12N5O5P/c9-8-11-6-5(7(14)12-8)10-3-13(6)1-2-18-4-19(15,16)17/h3H,1-2,4H2,(H2,15,16,17)(H3,9,11,12,14) Key: NZVORGQIEFTOQZ-UHFFFAOYSA-N
SMILES C1=NC2=C(N1CCOCP(=O)(O)O)NC(=NC2=O)N
Properties
Chemical formula	C₈H₁₂N₅O₅P
Molar mass	289.19 g·mol⁻¹
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

PMEG is an antiviral.^[1] GS-9191 and GS-9219 are PMEG pro-drugs.

References

↑ De Clercq, Erik (2013). "Dancing with chemical formulae of antivirals: A personal account". Biochemical Pharmacology 86 (6): 711–25. doi:10.1016/j.bcp.2013.07.012. PMID 23876344.

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