POU2AF1

POU class 2 associating factor 1

PDB rendering based on 1cqt.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols POU2AF1 ; BOB1; OBF-1; OBF1; OCAB
External IDs OMIM: 601206 MGI: 105086 HomoloGene: 4543 GeneCards: POU2AF1 Gene
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez 5450 18985
Ensembl ENSG00000110777 ENSMUSG00000032053
UniProt Q16633 Q64693
RefSeq (mRNA) NM_006235 NM_011136
RefSeq (protein) NP_006226 NP_035266
Location (UCSC) Chr 11:
111.35 – 111.46 Mb
Chr 9:
51.21 – 51.24 Mb
PubMed search

POU domain class 2-associating factor 1 is a protein that in humans is encoded by the POU2AF1 gene.[1][2]

Interactions

POU2AF1 has been shown to interact with:

References

  1. Junker S, Brøndum-Nielsen K, Newell JW, Matthias P, Tommerup N (Jun 1996). "Assignment of the human gene for Oct-binding factor-1 (OBF1), a B-cell-specific coactivator of octamer-binding transcription factors 1 and 2, to 11q23.1 by somatic cell hybridization and in situ hybridization". Genomics 33 (1): 143–5. doi:10.1006/geno.1996.0173. PMID 8617501.
  2. "Entrez Gene: POU2AF1 POU domain, class 2, associating factor 1".
  3. Chasman D, Cepek K, Sharp PA, Pabo CO (Oct 1999). "Crystal structure of an OCA-B peptide bound to an Oct-1 POU domain/octamer DNA complex: specific recognition of a protein-DNA interface". Genes Dev. 13 (20): 2650–7. doi:10.1101/gad.13.20.2650. PMC 317104. PMID 10541551.
  4. Wong MW, Henry RW, Ma B, Kobayashi R, Klages N, Matthias P, Strubin M, Hernandez N (Jan 1998). "The large subunit of basal transcription factor SNAPc is a Myb domain protein that interacts with Oct-1". Mol. Cell. Biol. 18 (1): 368–77. doi:10.1128/mcb.18.1.368. PMC 121507. PMID 9418884.
  5. Lee L, Stollar E, Chang J, Grossmann JG, O'Brien R, Ladbury J, Carpenter B, Roberts S, Luisi B (Jun 2001). "Expression of the Oct-1 transcription factor and characterization of its interactions with the Bob1 coactivator". Biochemistry 40 (22): 6580–8. doi:10.1021/bi010095x. PMID 11380252.
  6. Tiedt R, Bartholdy BA, Matthias G, Newell JW, Matthias P (Aug 2001). "The RING finger protein Siah-1 regulates the level of the transcriptional coactivator OBF-1". EMBO J. 20 (15): 4143–52. doi:10.1093/emboj/20.15.4143. PMC 149178. PMID 11483517.

Further reading


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