PPP2R3C

Protein phosphatase 2, regulatory subunit B, gamma
Identifiers
Symbols	PPP2R3C ; C14orf10; G4-1; G5pr
External IDs	OMIM: 615902 MGI: 1930009 HomoloGene: 9915 GeneCards: PPP2R3C Gene
Gene ontology Molecular function • protein binding • metal ion binding Cellular component • nucleus • cytoplasm • centrosome • spindle Biological process • microtubule cytoskeleton organization • B cell homeostasis • regulation of antimicrobial humoral response • cortical cytoskeleton organization • activation of protein kinase activity • T cell homeostasis • positive regulation of B cell differentiation • spleen development • regulation of mitochondrial depolarization Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	55012	59032
Ensembl	ENSG00000092020	ENSMUSG00000021022
UniProt	Q969Q6	Q9JK24
RefSeq (mRNA)	NM_001305155	NM_021529
RefSeq (protein)	NP_001292084	NP_067504
Location (UCSC)	Chr 14: 35.09 – 35.12 Mb	Chr 12: 55.28 – 55.3 Mb
PubMed search

Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma is an enzyme that in humans is encoded by the PPP2R3C gene.^[1][2][3]

References

1. Kono Y, Maeda K, Kuwahara K, Yamamoto H, Miyamoto E, Yonezawa K, Takagi K, Sakaguchi N (Aug 2002). "MCM3-binding GANP DNA-primase is associated with a novel phosphatase component G5PR". Genes Cells 7 (8): 821–34. doi:10.1046/j.1365-2443.2002.00562.x. PMID 12167160.
2. Xing Y, Igarashi H, Wang X, Sakaguchi N (Sep 2005). "Protein phosphatase subunit G5PR is needed for inhibition of B cell receptor–induced apoptosis". J Exp Med 202 (5): 707–19. doi:10.1084/jem.20050637. PMC 2212881. PMID 16129705.
3. "Entrez Gene: PPP2R3C protein phosphatase 2 (formerly 2A), regulatory subunit B'', gamma".

Further reading

• Kamnasaran D, Chen CP, Devriendt K, et al. (2005). "Defining a holoprosencephaly locus on human chromosome 14q13 and characterization of potential candidate genes". Genomics 85 (5): 608–21. doi:10.1016/j.ygeno.2005.01.010. PMID 15820313.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.