PTENP1

Phosphatase and tensin homolog pseudogene 1 (functional)
Identifiers
Symbols	PTENP1 ; PTEN-rs; PTEN2; PTENpg1; PTH2; psiPTEN
External IDs	OMIM: 613531 GeneCards: PTENP1 Gene
Gene ontology Molecular function • protein tyrosine/serine/threonine phosphatase activity • hydrolase activity Biological process • protein amino acid dephosphorylation
Orthologs
Species	Human	Mouse
Entrez	11191	n/a
Ensembl	ENSG00000237984	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	Chr 9: 33.67 – 33.68 Mb	n/a
PubMed search		n/a

Phosphatase and tensin homolog (mutated in multiple advanced cancers 1), pseudogene 1, also known as PTENP1, is a human gene.^[1]

References

1. "Entrez Gene: PTENP1 phosphatase and tensin homolog (mutated in multiple advanced cancers 1), pseudogene 1".

Further reading

• Kong D, Suzuki A, Zou TT, et al. (1997). "PTEN1 is frequently mutated in primary endometrial carcinomas". Nat. Genet. 17 (2): 143–4. doi:10.1038/ng1097-143. PMID 9326929.
• Teng DH, Hu R, Lin H, et al. (1998). "MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines". Cancer Res. 57 (23): 5221–5. PMID 9393738.
• Sakurada A, Suzuki A, Sato M, et al. (1998). "Infrequent genetic alterations of the PTEN/MMAC1 gene in Japanese patients with primary cancers of the breast, lung, pancreas, kidney, and ovary". Jpn. J. Cancer Res. 88 (11): 1025–8. doi:10.1111/j.1349-7006.1997.tb00324.x. PMID 9439675.
• Kim SK, Su LK, Oh Y, et al. (1998). "Alterations of PTEN/MMAC1, a candidate tumor suppressor gene, and its homologue, PTH2, in small cell lung cancer cell lines". Oncogene 16 (1): 89–93. doi:10.1038/sj.onc.1201512. PMID 9467947.
• Dahia PL, FitzGerald MG, Zhang X, et al. (1998). "A highly conserved processed PTEN pseudogene is located on chromosome band 9p21". Oncogene 16 (18): 2403–6. doi:10.1038/sj.onc.1201762. PMID 9620558.
• Forgacs E, Biesterveld EJ, Sekido Y, et al. (1998). "Mutation analysis of the PTEN/MMAC1 gene in lung cancer". Oncogene 17 (12): 1557–65. doi:10.1038/sj.onc.1202070. PMID 9794233.
• Fujii GH, Morimoto AM, Berson AE, Bolen JB (1999). "Transcriptional analysis of the PTEN/MMAC1 pseudogene, psiPTEN". Oncogene 18 (9): 1765–9. doi:10.1038/sj.onc.1202492. PMID 10208437.
• Trojan J, Plotz G, Brieger A, et al. (2002). "Activation of a cryptic splice site of PTEN and loss of heterozygosity in benign skin lesions in Cowden disease". J. Invest. Dermatol. 117 (6): 1650–3. doi:10.1046/j.0022-202x.2001.01954.x. PMID 11886535.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.