Pancreatic elastase II

Pancreatic elastase II
Identifiers
EC number 3.4.21.71
CAS number 75603-19-9
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Pancreatic elastase II (EC 3.4.21.71, pancreatic elastase 2) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction

Preferential cleavage: Leu-, Met- and Phe-. Hydrolyses elastin

This peptidase from trypsin family is formed by activation of proelastase II from mammalian pancreas by trypsin.

References

  1. Fletcher, T.S., Shen, W.-F. and Largman, C. (1987). "Primary structure of human pancreatic elastase 2 determined by sequence analysis of the cloned mRNA". Biochemistry 26: 7256–7261. doi:10.1021/bi00397a010. PMID 3427074.
  2. Shirasu, Y., Yoshida, H., Matsuki, S., Takemura, K., Ikeda, N., Shimada, Y., Ozawa, T., Mikayama, T., Iijima, H., Ishida, A., Sato, Y., Tamai, Y., Tanaka, J. and Ikenaga, H. (1987). "Molecular cloning and expression in Escherichia coli of a cDNA encoding human pancreatic elastase 2". J. Biochem. (Tokyo) 102 (6): 1555–1563. PMID 2834346.

External links

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