Phosphoacetylglucosamine mutase

phosphoacetylglucosamine mutase
Identifiers
EC number 5.4.2.3
CAS number 9027-51-4
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a phosphoacetylglucosamine mutase (EC 5.4.2.3) is an enzyme that catalyzes the chemical reaction

N-acetyl-alpha-D-glucosamine 1-phosphate \rightleftharpoons N-acetyl-D-glucosamine 6-phosphate

Hence, this enzyme has one substrate, N-acetyl-alpha-D-glucosamine 1-phosphate, and one product, N-acetyl-D-glucosamine 6-phosphate.

This enzyme belongs to the family of isomerases, specifically the phosphotransferases (phosphomutases), which transfer phosphate groups within a molecule. The systematic name of this enzyme class is N-acetyl-alpha-D-glucosamine 1,6-phosphomutase. Other names in common use include acetylglucosamine phosphomutase, acetylglucosamine phosphomutase, acetylaminodeoxyglucose phosphomutase, phospho-N-acetylglucosamine mutase, and N-acetyl-D-glucosamine 1,6-phosphomutase. This enzyme participates in aminosugars metabolism. This enzyme has at least one effector, N-Acetyl-D-glucosamine 1,6-bisphosphate.

Structural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes 1WJW, 2DKA, 2DKC, and 2DKD.

References


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