Pinocembrin

Pinocembrin

Names
IUPAC name (2S)-5,7-dihydroxy-2-phenyl-2,3-dihydro-4H-chromen-4-one
Other names Dihydrochrysin Galangin flavanone 5,7-Dihydroxyflavanone 5,7-dihydroxy-2-phenyl-2,3-dihydro-4H-chromen-4-one 4H-1-benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-phenyl- 5,7-Dihydroxy-2-phenyl-chroman-4-one
Identifiers
CAS Number	480-39-7
ChEBI	CHEBI:28157
ChEMBL	ChEMBL399910
ChemSpider	208593
Jmol interactive 3D	Image
PubChem	238782
InChI InChI=1S/C15H12O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-7,13,16-17H,8H2 Key: URFCJEUYXNAHFI-UHFFFAOYSA-N InChI=1/C15H12O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-7,13,16-17H,8H2 Key: URFCJEUYXNAHFI-UHFFFAOYAA
SMILES O=C2c3c(OC(c1ccccc1)C2)cc(O)cc3O
Properties
Chemical formula	C15H12O4
Molar mass	256.25 g/mol
Density	1.386 g/mL
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Pinocembrin is a flavanone, a type of flavonoid. It is an antioxidant found in damiana,^[1] honey, fingerroot,^[2] and propolis.^[3]

Pinocembrin can be converted biosynthetically to pinobanksin by hydroxylation adjacent to the ketone.

See also

• Pinobanksin

References

1. Zhao, J; Dasmahapatra AK; Khan SI; Khan IA (Dec 2008). "Anti-aromatase activity of the constituents from damiana (Turnera diffusa)". J Ethnopharmacol 120 (3): 387–393. doi:10.1016/j.jep.2008.09.016. PMID 18948180.
2. Punvittayagul, C; Wongpoomchai R; Taya S; Pompimon W. (January 2011). "Effect of pinocembrin isolated from Boesenbergia pandurata on xenobiotic-metabolizing enzymes in rat liver.". Drug Metabolism Letters 5 (1): 1–5. doi:10.2174/187231211794455226. PMID 20942797. Retrieved 2013-04-24.
3. Bosio K, Avanzini C, D’Avolio A, Ozino O, Savoia D (2000). "In vitro activity of propolis against Streptococcus pyogenes". Letters in Applied Microbiology 31 (2): 174–177. doi:10.1046/j.1365-2672.2000.00785.x. PMID 10972723.