Pirquinozol
 | |
| Systematic (IUPAC) name | |
|---|---|
|
2-(hydroxymethyl)pyrazolo[1,5-c]quinazolin-5(6H)-one | |
| Clinical data | |
| Legal status |
|
| Routes of administration | Oral |
| Identifiers | |
| CAS Number | 65950-99-4 |
| ATC code | None |
| PubChem | CID 47783 |
| ChemSpider | 11317704 |
| UNII |
D16HG4V2UC  |
| KEGG | D05516 |
| Chemical data | |
| Formula | C11H9N3O2 |
| Molar mass | 215.21 g/mol |
| |
Pirquinozol (SQ-13,847) is a drug which was investigated as an antiallergen and antiasthmatic agent in the early 1980s but was never marketed.[1][2][3] Notably, pirquinozol is not an antihistamine, though it does block the release of histamine evoked by allergens, and it does not bind to β-adrenergic receptors either.[1]
References
- 1 2 Free CA, Hall LE (June 1980). "Antiallergic properties of SQ 13,847, an orally effective agent. II. Activity in vitro". The Journal of Pharmacology and Experimental Therapeutics 213 (3): 437–40. PMID 6162946.
- ↑ Casey FB, Abboa-Offei BE, Marretta J (June 1980). "Antiallergic properties of SQ 13,847, an orally effective agent. I. Activity in vivo". The Journal of Pharmacology and Experimental Therapeutics 213 (3): 432–6. PMID 7205610.
- ↑ Casey FB, Abboa-Offei BE (June 1983). "Anti-allergic properties of pirquinozol (SQ 13,847) an orally effective agent. Evaluation in an anti-IgE-induced pulmonary function model in rats". The Journal of Pharmacy and Pharmacology 35 (6): 394–6. doi:10.1111/j.2042-7158.1983.tb02967.x. PMID 6135784.
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