Platelet receptor Gi24

Chromosome 10 open reading frame 54
Identifiers
Symbols	C10orf54 ; B7-H5; B7H5; GI24; PP2135; SISP1
External IDs	OMIM: 615608 MGI: 1921298 HomoloGene: 81923 GeneCards: C10orf54 Gene
Gene ontology Molecular function • receptor activity Cellular component • external side of plasma membrane • integral component of membrane Biological process • negative regulation of T cell cytokine production • BMP signaling pathway • positive regulation of BMP signaling pathway • stem cell differentiation • negative regulation of CD4-positive, alpha-beta T cell proliferation • positive regulation of stem cell differentiation Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	64115	74048
Ensembl	ENSG00000107738	ENSMUSG00000020101
UniProt	Q9H7M9	Q9D659
RefSeq (mRNA)	NM_022153	NM_001159572
RefSeq (protein)	NP_071436	NP_001153044
Location (UCSC)	Chr 10: 71.75 – 71.77 Mb	Chr 10: 60.35 – 60.37 Mb
PubMed search

Platelet receptor Gi24 is a protein that in humans is encoded by the C10orf54 gene.^[1][2]

References

1. Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D, Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS, Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M, Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J, Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard A, Wood WI, Godowski P, Gray A (Oct 2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
2. "Entrez Gene: C10orf54 chromosome 10 open reading frame 54".

Further reading

• Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway.". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
• Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites.". Protein Sci. 13 (10): 2819–24. doi:10.1110/ps.04682504. PMC 2286551. PMID 15340161.
• Wan D, Gong Y, Qin W, et al. (2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression.". Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15724–9. doi:10.1073/pnas.0404089101. PMC 524842. PMID 15498874.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.