Benzylpenicilloyl polylysine
.png) | |
| Systematic (IUPAC) name | |
|---|---|
|
[2S-(2α,5α,6β)]-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate : L-Lysine homopolymer | |
| Clinical data | |
| Trade names | Pre-Pen |
| Licence data | US FDA:link |
| Legal status |
|
| Routes of administration | Liquid intradermal |
| Identifiers | |
| CAS Number |
31855-75-1  |
| ATC code | None |
| DrugBank |
DB00895 |
| ChemSpider | none |
| ChEMBL |
CHEMBL1201779 |
| Synonyms | Pre-Pen |
 (what is this?) (verify) | |
Benzylpenicilloyl polylysine (Pre-Pen) is used as a skin test before the administration of penicillin. It is used to detect the immunoglobulin E antibodies.[1][2] The chemical structure consists of the benzylpenicilloyl group attached to a polymer of L-lysine.[3][4][5]
References
- ↑ http://www.pharmgkb.org/do/serve?objId=PA164754810&objCls=Drug
- ↑ http://www.drugbank.ca/drugs/DB00895
- ↑ Vemuri, Preeti; Harris, Kathleen E.; Suh, Lydia A.; Grammer, Leslie C. (2004). "Preparation of benzylpenicilloyl-polylysine: a preliminary study". Allergy and Asthma Proceedings 25 (3): 165–168.
- ↑ Goldschmidt, BM; BB Levine (1983). "The preparation and determination of structure of benzylpenicilloyl compounds used in skin-testing for penicillin allergy.". Journal of Antibiotics 36 (6): 709–14. doi:10.7164/antibiotics.36.709. PMID 6874593.
- ↑ http://ainotes.wikispaces.com/file/view/PREPEN_Package_Insert.pdf
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