Prospidium chloride

Prospidium chloride
Names
IUPAC name
1-chloro-3-[12-(3-chloro-2-hydroxypropyl)-3,12-diaza-6,9-diazoniadispiro[5.2.59.26]hexadecan-3-yl]propan-2-ol dichloride
Other names
Prospidine
Identifiers
23476-83-7 YesY
ChEMBL ChEMBL509176 N
Jmol interactive 3D Image
PubChem 78921313
UNII 7G733H6RES N
Properties
C18H36Cl4N4O2
Molar mass 482.31 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

Prospidium chloride is a spiro compound.


Definition of Prospidin: A Russian Drug, a dispiropiperazine derivative with potential cytostatic, anti-inflammatory and immune-suppressive properties. Although the exact mechanism of action of prospidin is not known, this agent was shown to interact with DNA, disrupting cell cycle at G2 phase, inhibiting phagocytic activity of monocytes and macrophages. This compound had a registration for Squamous Cell Carcinoma of the Head&Neck, reports exist about its activity in HIV-Related Kaposi Sarcoma. Prospidin has good anti-lupus activity due to its immunosuppressant effects and was also used in refractory Rheumatoid Arthritis as an anti-rheumatic drug. Usually, it has no Hematologic Toxicity. (NCI04) Prospidin is from the group

DNA Adduct Forming Agent Immunosuppressant

Other Names for Prospidin

Prospidin

3,12-Diaza-6,9-diazoniadispiro(5.2.5.2)hexadecane, 3,12-bis(3-chloro-2-hydroxypropyl)-, dichloride

Prospidine

Prospidium

Prospidium Chloride

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