Prostaglandin E
PGE1 - Alprostadil
PGE2 - Dinoprostone
Prostaglandin E is a family of naturally occurring prostaglandins and may be used pharmaceutically in medicine.
Types include:
- Prostaglandin E1 also termed Alprostadil
- Prostaglandin E2 also termed Dinoprostone
It is created from prostaglandin E synthase.
It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.[1]
Prostaglandin E2
Prostaglandin E2 is secreted in microvessels by the endothelium. It is a direct vasodilator and it inhibits the release of noradrenaline from sympathetic nerve terminals. It doesn't have the effect on platelets PGI2 does.
References
- ↑ "WHO Model List of EssentialMedicines" (PDF). World Health Organization. October 2013. Retrieved 22 April 2014.
Pharmacology 2007. Rang, Dale, Ritter, Flower. Churchill Livingstone Elsevier.
External links
- Prostaglandins E at the US National Library of Medicine Medical Subject Headings (MeSH)
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