Proteus phenomenon

This article is about a statistical bias in academic publishing. For the aspect of human psychology, see Proteus effect.

The Proteus phenomenon is the greater tendency in science for early replications of a work to contradict the original findings, a consequence of publication bias.[1] It is akin to the winner's curse.[2]

The term was coined by John P. A. Ioannidis and Thomas A. Trikalinos in 2005 named after the Greek god Proteus who could rapidly change his appearance.[3] A 2013 paper argued that the phenomenon might be "desirable or even optimal" from a scientific standpoint.[4]

See also

References

  1. ↑ Pfeiffer, Thomas, Lars Bertram, and John Ioannidis. "Quantifying selective reporting and the Proteus phenomenon for multiple datasets with similar bias." PloS one 6.3 (2011): e18362.
  2. ↑ Button, Katherine S., et al. "Power failure: why small sample size undermines the reliability of neuroscience." Nature Reviews Neuroscience 14.5 (2013): 365–376.
  3. ↑ Ioannidis JP, Trikalinos TA (2005) Early extreme contradictory estimates may appear in published research: The Proteus phenomenon in molecular genetics research and randomized trials. J Clin Epidemiol 58: 543–549.
  4. ↑ de Winter, Joost; Happee, Riender; Wray, K. Brad (20 June 2013). "Why Selective Publication of Statistically Significant Results Can Be Effective". PLoS ONE 8 (6): e66463. doi:10.1371/journal.pone.0066463.
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