Quassin
 | |
| Names | |
|---|---|
| IUPAC name
2,12-dimethoxypicrasa-2,12-diene-1,11,16-trione | |
| Other names
(3aS,6aR,7aS,8S,11aS,11bS,11cS) -1,3a,4,5,6a,7,7a,8,11,11a,11b,11c-dodecahydro-2,10-dimethoxy-3,8,11a,11c- tetramethyldibenzo[de,g]chromene-1,5,11-trione | |
| Identifiers | |
76-78-8  | |
| ChEMBL | ChEMBL517016  |
| ChemSpider | 59014 |
| EC Number | 200-985-9 |
| Jmol interactive 3D | Image |
| PubChem | 65571 |
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| Properties | |
| C22H28O6 | |
| Molar mass | 388.46 g·mol−1 |
| Appearance | White crystalline substance |
| Melting point | 200 to 222 °C (392 to 432 °F; 473 to 495 K) |
| Boiling point | 586 °C (1,087 °F; 859 K) |
| Insoluble | |
| Vapor pressure | 13 mmHg (@25 °C) |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| verify (what is ?) | |
| Infobox references | |
Quassin is a white bitter, crystalline substance extracted from the quassia tree. It is one of the most bitter substances found in nature with a bitter threshold of 0.08 ppm and it is 50 times more bitter than quinine.[1]
Quassin is used as a medicine in traditional Chinese medicine.
Extracts of the Bitter tree (or bitter wood) (Quassia amara L. or Picrasma excelsa) are also used as additives in soft drinks.[1]
Although its skeleton possesses 20 carbon atoms, quassin is not a diterpene but rather a triterpene lactone, which derives from euphol by loss of 10 carbon atoms including C4.
References
- 1 2 Scientific Committee on Food Opinion of the Scientific Committee on Food on quassin (expressed on 2 July 2002). SCF/CS/FLAV/FLAVOUR/29 Final
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