RAB13

RAB13, member RAS oncogene family
Identifiers
Symbols	RAB13 ; GIG4
External IDs	OMIM: 602672 MGI: 1927232 HomoloGene: 113882 GeneCards: RAB13 Gene
Gene ontology Molecular function • GTPase activity • protein binding • GTP binding Cellular component • cytoplasm • Golgi apparatus • trans-Golgi network • plasma membrane • bicellular tight junction • lateral plasma membrane • lamellipodium • endocytic vesicle • transport vesicle membrane • cytoplasmic vesicle membrane • cytoplasmic vesicle • insulin-responsive compartment • neuron projection • recycling endosome • recycling endosome membrane • extracellular exosome Biological process • intracellular protein transport • protein kinase A signaling • endosomal transport • cortical actin cytoskeleton organization • neuron projection development • endocytic recycling • Rab protein signal transduction • cellular response to insulin stimulus • endothelial cell chemotaxis • trans-Golgi network to recycling endosome transport • membrane organization • bicellular tight junction assembly • establishment of protein localization to plasma membrane • establishment of Sertoli cell barrier • protein localization to cell leading edge Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	5872	68328
Ensembl	ENSG00000143545	ENSMUSG00000027935
UniProt	P51153	Q9DD03
RefSeq (mRNA)	NM_001272038	NM_001293741
RefSeq (protein)	NP_001258967	NP_001280670
Location (UCSC)	Chr 1: 153.98 – 153.99 Mb	Chr 3: 90.21 – 90.23 Mb
PubMed search

Ras-related protein Rab-13 is a protein that in humans is encoded by the RAB13 gene.^[1][2]

References

1. Zahraoui A, Joberty G, Arpin M, Fontaine JJ, Hellio R, Tavitian A, Louvard D (Feb 1994). "A small rab GTPase is distributed in cytoplasmic vesicles in non polarized cells but colocalizes with the tight junction marker ZO-1 in polarized epithelial cells". J Cell Biol 124 (1–2): 101–15. doi:10.1083/jcb.124.1.101. PMC 2119893. PMID 8294494.
2. "Entrez Gene: RAB13 RAB13, member RAS oncogene family".

Further reading

• Joberty G, Tavitian A, Zahraoui A (1993). "Isoprenylation of Rab proteins possessing a C-terminal CaaX motif". FEBS Lett. 330 (3): 323–8. doi:10.1016/0014-5793(93)80897-4. PMID 8375503.
• Leek JP, Hamlin PJ, Wilton J, Lench NJ (1998). "Assignment of the Rab13 gene (RAB13) to human chromosome band 12q13 by in situ hybridization". Cytogenet. Cell Genet. 79 (3–4): 210–1. doi:10.1159/000134724. PMID 9605854.
• Marzesco AM, Galli T, Louvard D, Zahraoui A (1998). "The rod cGMP phosphodiesterase delta subunit dissociates the small GTPase Rab13 from membranes". J. Biol. Chem. 273 (35): 22340–5. doi:10.1074/jbc.273.35.22340. PMID 9712853.
• Bao S, Zhu J, Garvey WT (1999). "Cloning of Rab GTPases expressed in human skeletal muscle: studies in insulin-resistant subjects". Horm. Metab. Res. 30 (11): 656–62. doi:10.1055/s-2007-978953. PMID 9918381.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Morimoto S, Nishimura N, Terai T, et al. (2005). "Rab13 mediates the continuous endocytic recycling of occludin to the cell surface". J. Biol. Chem. 280 (3): 2220–8. doi:10.1074/jbc.M406906200. PMID 15528189.
• Barrios-Rodiles M, Brown KR, Ozdamar B, et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science 307 (5715): 1621–5. doi:10.1126/science.1105776. PMID 15761153.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.