RAB15

RAB15, member RAS oncogene family
Identifiers
Symbol	RAB15
External IDs	HomoloGene: 131279 GeneCards: RAB15 Gene
Gene ontology Molecular function • GTPase activity • protein binding • GTP binding Cellular component • cytoplasm • plasma membrane • endosome membrane • perinuclear region of cytoplasm • extracellular exosome • primary cilium Biological process • intracellular protein transport • vesicle docking involved in exocytosis • protein secretion • Rab protein signal transduction • protein localization to plasma membrane • positive regulation of regulated secretory pathway Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	376267	n/a
Ensembl	ENSG00000139998	n/a
UniProt	P59190	n/a
RefSeq (mRNA)	NM_001308154	n/a
RefSeq (protein)	NP_001295083	n/a
Location (UCSC)	Chr 14: 64.95 – 64.97 Mb	n/a
PubMed search		n/a

Ras-related protein Rab-15 is a protein that in humans is encoded by the RAB15 gene.^[1][2]

References

1. Pereira-Leal JB, Seabra MC (Nov 2001). "Evolution of the Rab family of small GTP-binding proteins". J Mol Biol 313 (4): 889–901. doi:10.1006/jmbi.2001.5072. PMID 11697911.
2. "Entrez Gene: RAB15 RAB15, member RAS onocogene family".

Further reading

• Zuk PA, Elferink LA (1999). "Rab15 mediates an early endocytic event in Chinese hamster ovary cells.". J. Biol. Chem. 274 (32): 22303–12. doi:10.1074/jbc.274.32.22303. PMID 10428799.
• Zuk PA, Elferink LA (2000). "Rab15 differentially regulates early endocytic trafficking.". J. Biol. Chem. 275 (35): 26754–64. doi:10.1074/jbc.M000344200. PMID 10837464.
• Strick DJ, Francescutti DM, Zhao Y, Elferink LA (2002). "Mammalian suppressor of Sec4 modulates the inhibitory effect of Rab15 during early endocytosis.". J. Biol. Chem. 277 (36): 32722–9. doi:10.1074/jbc.M205101200. PMID 12105226.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Heilig R, Eckenberg R, Petit JL, et al. (2003). "The DNA sequence and analysis of human chromosome 14.". Nature 421 (6923): 601–7. doi:10.1038/nature01348. PMID 12508121.
• Fukuda M (2003). "Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2.". J. Biol. Chem. 278 (17): 15373–80. doi:10.1074/jbc.M212341200. PMID 12578829.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Strick DJ, Elferink LA (2006). "Rab15 effector protein: a novel protein for receptor recycling from the endocytic recycling compartment.". Mol. Biol. Cell 16 (12): 5699–709. doi:10.1091/mbc.E05-03-0204. PMC 1289414. PMID 16195351.