RAB37

RAB37, member RAS oncogene family
Identifiers
Symbols	RAB37 ; FLJ30284; FLJ32507
External IDs	OMIM: 609956 MGI: 1929945 HomoloGene: 23303 GeneCards: RAB37 Gene
Gene ontology Molecular function • GTPase activity • protein binding • GTP binding Cellular component • endosome • endoplasmic reticulum-Golgi intermediate compartment • plasma membrane • secretory granule membrane Biological process • intracellular protein transport • vesicle docking involved in exocytosis • protein secretion • regulation of exocytosis • Rab protein signal transduction • protein localization to plasma membrane Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	326624	58222
Ensembl	ENSG00000172794	ENSMUSG00000020732
UniProt	Q96AX2	Q9JKM7
RefSeq (mRNA)	NM_001006637	NM_001163753
RefSeq (protein)	NP_001006639	NP_001157225
Location (UCSC)	Chr 17: 74.67 – 74.75 Mb	Chr 11: 115.09 – 115.16 Mb
PubMed search

Ras-related protein Rab-37 is a protein that in humans is encoded by the RAB37 gene.^[1][2]

Rab proteins are low molecular mass GTPases that are critical regulators of vesicle trafficking. For additional background information on Rab proteins, see MIM 179508.[supplied by OMIM]^[2]

References

1. Masuda ES, Luo Y, Young C, Shen M, Rossi AB, Huang BC, Yu S, Bennett MK, Payan DG, Scheller RH (May 2000). "Rab37 is a novel mast cell specific GTPase localized to secretory granules". FEBS Lett 470 (1): 61–4. doi:10.1016/S0014-5793(00)01288-6. PMID 10722846.
2. "Entrez Gene: RAB37 RAB37, member RAS oncogene family".

Further reading

• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Breuza L, Halbeisen R, Jenö P, et al. (2004). "Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46.". J. Biol. Chem. 279 (45): 47242–53. doi:10.1074/jbc.M406644200. PMID 15308636.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gevaert K, Goethals M, Martens L, et al. (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.". Nat. Biotechnol. 21 (5): 566–9. doi:10.1038/nbt810. PMID 12665801.
• Fukuda M (2003). "Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2.". J. Biol. Chem. 278 (17): 15373–80. doi:10.1074/jbc.M212341200. PMID 12578829.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.