REEP1

Receptor accessory protein 1
Identifiers
Symbols	REEP1 ; C2orf23; HMN5B; SPG31
External IDs	OMIM: 609139 MGI: 1098827 HomoloGene: 41504 GeneCards: REEP1 Gene
Gene ontology Molecular function • protein binding • microtubule binding • olfactory receptor binding Cellular component • cytoplasm • endoplasmic reticulum • endoplasmic reticulum membrane • membrane • integral component of membrane • mitochondrial membrane Biological process • regulation of intracellular transport • protein insertion into membrane • endoplasmic reticulum tubular network organization Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	65055	52250
Ensembl	ENSG00000068615	ENSMUSG00000052852
UniProt	Q9H902	Q8BGH4
RefSeq (mRNA)	NM_001164730	NM_178608
RefSeq (protein)	NP_001158202	NP_848723
Location (UCSC)	Chr 2: 86.21 – 86.34 Mb	Chr 6: 71.71 – 71.81 Mb
PubMed search

Receptor expression-enhancing protein 1 is a protein that in humans is encoded by the REEP1 gene.^[1][2][3]

References

1. Clark AJ, Metherell LA, Cheetham ME, Huebner A (Nov 2005). "Inherited ACTH insensitivity illuminates the mechanisms of ACTH action". Trends Endocrinol Metab 16 (10): 451–7. doi:10.1016/j.tem.2005.10.006. PMID 16271481.
2. Saito H, Kubota M, Roberts RW, Chi Q, Matsunami H (Nov 2004). "RTP family members induce functional expression of mammalian odorant receptors". Cell 119 (5): 679–91. doi:10.1016/j.cell.2004.11.021. PMID 15550249.
3. "Entrez Gene: REEP1 receptor accessory protein 1".

Further reading

• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain.". Mol. Cell Proteomics 3 (11): 1093–101. doi:10.1074/mcp.M400085-MCP200. PMID 15345747.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4.". Nature 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621.
• Behrens M, Bartelt J, Reichling C, et al. (2006). "Members of RTP and REEP gene families influence functional bitter taste receptor expression.". J. Biol. Chem. 281 (29): 20650–9. doi:10.1074/jbc.M513637200. PMID 16720576.
• Züchner S, Wang G, Tran-Viet KN, et al. (2006). "Mutations in the novel mitochondrial protein REEP1 cause hereditary spastic paraplegia type 31.". Am. J. Hum. Genet. 79 (2): 365–9. doi:10.1086/505361. PMC 1559498. PMID 16826527.