RNF24
| Ring finger protein 24 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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| Identifiers | |||||||||||||
| Symbols | RNF24 ; G1L | ||||||||||||
| External IDs | OMIM: 612489 MGI: 1261771 HomoloGene: 5223 GeneCards: RNF24 Gene | ||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 11237 | 51902 | |||||||||||
| Ensembl | ENSG00000101236 | ENSMUSG00000048911 | |||||||||||
| UniProt | Q9Y225 | Q8BGI1 | |||||||||||
| RefSeq (mRNA) | NM_001134337 | NM_178607 | |||||||||||
| RefSeq (protein) | NP_001127809 | NP_848722 | |||||||||||
| Location (UCSC) |
Chr 20: 3.93 – 4.02 Mb |
Chr 2: 131.3 – 131.35 Mb | |||||||||||
| PubMed search | |||||||||||||
Ring finger protein 24 is a protein that in humans is encoded by the RNF24 gene.[1][2]
RNF24 binds TRPC6 (603652) and other transient receptor potential cation channel (TRPC) family members and is involved in regulation of intracellular trafficking of TRPCs.[2] In addition, RNF24 contains similarity to the Drosophila goliath protein and thus may function as a transcription factor.[1]
References
- 1 2 "Entrez Gene: ring finger protein 24".
- 1 2 Lussier MP, Lepage PK, Bousquet SM, Boulay G (May 2008). "RNF24, a new TRPC interacting protein, causes the intracellular retention of TRPC". Cell Calcium 43 (5): 432–43. doi:10.1016/j.ceca.2007.07.009. PMID 17850865.
Further reading
- Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Zhang QH, Ye M, Wu XY, et al. (2000). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
- Deloukas P, Matthews LH, Ashurst J, et al. "The DNA sequence and comparative analysis of human chromosome 20.". Nature 414 (6866): 865–71. doi:10.1038/414865a. PMID 11780052.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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