RPL37

Ribosomal protein L37
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 4V6X​, 5AJ0​
Identifiers
Symbols	RPL37 ; L37
External IDs	OMIM: 604181 MGI: 1914531 HomoloGene: 68110 GeneCards: RPL37 Gene
Gene ontology Molecular function • RNA binding • structural constituent of ribosome • rRNA binding • metal ion binding Cellular component • cytosol • cytosolic large ribosomal subunit Biological process • nuclear-transcribed mRNA catabolic process, nonsense-mediated decay • translation • translational initiation • translational elongation • translational termination • SRP-dependent cotranslational protein targeting to membrane • gene expression • viral process • viral life cycle • viral transcription • cellular protein metabolic process Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	6167	67281
Ensembl	ENSG00000145592	ENSMUSG00000041841
UniProt	P61927	Q9D823
RefSeq (mRNA)	NM_000997	NM_026069
RefSeq (protein)	NP_000988	NP_080345
Location (UCSC)	Chr 5: 40.83 – 40.84 Mb	Chr 15: 5.12 – 5.12 Mb
PubMed search

60S ribosomal protein L37 is a protein that in humans is encoded by the RPL37 gene.^[1][2][3]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L37E family of ribosomal proteins. It is located in the cytoplasm. The protein contains a C2C2-type zinc finger-like motif. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.^[3]

References

1. Barnard GF, Staniunas RJ, Puder M, Steele GD Jr, Chen LB (Sep 1994). "Human ribosomal protein L37 has motifs predicting serine/threonine phosphorylation and a zinc-finger domain". Biochim Biophys Acta 1218 (3): 425–8. doi:10.1016/0167-4781(94)90197-x. PMID 7545944.
2. Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC (Aug 1998). "A map of 75 human ribosomal protein genes". Genome Res 8 (5): 509–23. doi:10.1101/gr.8.5.509. PMID 9582194.
3. "Entrez Gene: RPL37 ribosomal protein L37".

Further reading

• Wool IG, Chan YL, Glück A (1996). "Structure and evolution of mammalian ribosomal proteins.". Biochem. Cell Biol. 73 (11–12): 933–47. doi:10.1139/o95-101. PMID 8722009.
• Su S, Bird RC (1995). "Cell cycle, differentiation and tissue-independent expression of ribosomal protein L37". Eur. J. Biochem. 232 (3): 789–97. doi:10.1111/j.1432-1033.1995.tb20874.x. PMID 7588717.
• Uechi T, Tanaka T, Kenmochi N (2001). "A complete map of the human ribosomal protein genes: assignment of 80 genes to the cytogenetic map and implications for human disorders". Genomics 72 (3): 223–30. doi:10.1006/geno.2000.6470. PMID 11401437.
• Yoshihama M, Uechi T, Asakawa S, et al. (2002). "The Human Ribosomal Protein Genes: Sequencing and Comparative Analysis of 73 Genes". Genome Res. 12 (3): 379–90. doi:10.1101/gr.214202. PMC 155282. PMID 11875025.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Schwartz EI, Intine RV, Maraia RJ (2004). "CK2 Is Responsible for Phosphorylation of Human La Protein Serine-366 and Can Modulate rpL37 5′-Terminal Oligopyrimidine mRNA Metabolism". Mol. Cell. Biol. 24 (21): 9580–91. doi:10.1128/MCB.24.21.9580-9591.2004. PMC 522270. PMID 15485924.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.