RPL9

Ribosomal protein L9
PDB rendering based on 2cql.
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 2CQL​, 4V6X​, 5AJ0​
Identifiers
Symbols	RPL9 ; L9; NPC-A-16
External IDs	OMIM: 603686 MGI: 1298373 HomoloGene: 90855 GeneCards: RPL9 Gene
Gene ontology Molecular function • RNA binding • structural constituent of ribosome • protein binding • rRNA binding Cellular component • nucleus • nucleolus • cytoplasm • cytosol • ribosome • focal adhesion • membrane • cytosolic large ribosomal subunit Biological process • nuclear-transcribed mRNA catabolic process, nonsense-mediated decay • cytoplasmic translation • translation • translational initiation • translational elongation • translational termination • SRP-dependent cotranslational protein targeting to membrane • gene expression • viral process • viral life cycle • viral transcription • cellular protein metabolic process Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	6133	20005
Ensembl	ENSG00000163682	ENSMUSG00000047215
UniProt	P32969	P51410
RefSeq (mRNA)	NM_000661	NM_011292
RefSeq (protein)	NP_000652	NP_035422
Location (UCSC)	Chr 4: 39.45 – 39.46 Mb	Chr 5: 65.39 – 65.39 Mb
PubMed search

60S ribosomal protein L9 is a protein that in humans is encoded by the RPL9 gene.^[1][2][3]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L6P family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.^[3]

References

1. Mazuruk K, Schoen TJ, Chader GJ, Iwata T, Rodriguez IR (Apr 1996). "Structural organization and chromosomal localization of the human ribosomal protein L9 gene". Biochim Biophys Acta 1305 (3): 151–62. doi:10.1016/0167-4781(95)00201-4. PMID 8597601.
2. Hori N, Murakawa K, Matoba R, Fukushima A, Okubo K, Matsubara K (Nov 1993). "A new human ribosomal protein sequence, homologue of rat L9". Nucleic Acids Res 21 (18): 4395. doi:10.1093/nar/21.18.4395. PMC 310081. PMID 8415001.
3. "Entrez Gene: RPL9 ribosomal protein L9".

Further reading

• Wool IG, Chan YL, Glück A (1996). "Structure and evolution of mammalian ribosomal proteins.". Biochem. Cell Biol. 73 (11–12): 933–47. doi:10.1139/o95-101. PMID 8722009.
• Kenmochi N, Kawaguchi T, Rozen S, et al. (1998). "A map of 75 human ribosomal protein genes". Genome Res. 8 (5): 509–23. doi:10.1101/gr.8.5.509. PMID 9582194.
• Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature 433 (7021): 77–83. doi:10.1038/nature03207. PMID 15635413.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
• Oh JH, Yang JO, Hahn Y, et al. (2006). "Transcriptome analysis of human gastric cancer". Mamm. Genome 16 (12): 942–54. doi:10.1007/s00335-005-0075-2. PMID 16341674.