Rescue fusion hybridization

Rescue fusion hybridization is a process used to manufacture some therapeutic cancer vaccines in which individual tumor cells obtained through biopsy are fused with an antibody-secreting cell to form a heterohybridoma. This cell then secretes the unique idiotype, or immunoglobulin antigen characteristic of the individual tumor, which is purified for use as the vaccine.[1]

It is used to produce the BiovaxID vaccine for follicular lymphoma.

References

  1. ↑ "What Comes After Dendreon’s Provenge?". 18 Oct 2010.


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