List of highways numbered 408

Route 408 or Highway 408 may refer to:

Canada

• Manitoba Provincial Road 408

Japan

• Japan National Route 408

United States

• Florida State Road 408
• Georgia State Route 408 (unsigned designation for Interstate 475
• Louisiana Highway 408
• Maryland Route 408
  • Maryland Route 408
• New York:
  • New York State Route 408
    • New York State Route 408A (former)
  • New York State Route 408 (former)
  • County Route 408 (Albany County, New York)
  • County Route 408 (Erie County, New York)
• Pennsylvania Route 408
• Texas State Highway Spur 408
• Virginia State Route 408 (former)