Ruth Sonntag Nussenzweig
Ruth Sonntag Nussenzweig was the C.V. Starr Professor of Medical And Molecular Parasitology at NYU, a specialist in the development of Malaria vaccines. She is now Research Professor, in NYU's Department of Pathology and Professor Emerita of Microbiology and Pathology, in NYU's Department of Microbiology.
Biography
Nussenzweig received a M.D from University of Sao Paulo, School of Medicine, Sao Paulo, Brazil,[1]
In 1967 she demonstrated that mice could acquire immunity to the Plasmodium berghei parasite by exposing them to sporozoites that had been inactivated by irradiated by x-rays.[2]
Major recent publications
Huang, Jing; Li, Xiangming; Coelho-Dos-Reis, Jordana G A; Zhang, Min; Mitchell, Robert; Nogueira, Raquel Tayar; Tsao, Tiffany; Noe, Amy R; Ayala, Ramses; Sahi, Vincent; Gutierrez, Gabriel M; Nussenzweig, Victor; Wilson, James M; Nardin, Elizabeth H; Nussenzweig, Ruth S; Tsuji, Moriya. "Human immune system mice immunized with Plasmodium falciparum circumsporozoite protein induce protective human humoral immunity against malaria." Journal of Immunological Methods. 2015 Sep;:42-50
Teixeira, Lais H; Tararam, Cibele A; Lasaro, Marcio O; Camacho, Ariane G A; Ersching, Jonatan; Leal, Monica T; Herrera, Socrates; Bruna-Romero, Oscar; Soares, Irene S; Nussenzweig, Ruth S; Ertl, Hildegund C J; Nussenzweig, Victor; Rodrigues, Mauricio M. "Immunogenicity of a Prime-Boost Vaccine Containing the Circumsporozoite Proteins of Plasmodium vivax in Rodents. Infection & Immunity. 2014 Feb;82(2):793-807
Mishra, Satish; Nussenzweig, Ruth S; Nussenzweig, Victor. "Antibodies to Plasmodium circumsporozoite protein (CSP) inhibit sporozoite's cell traversal activity." Journal of Immunological Methods. 2012 Mar;377(1-2):47-52
Camacho, Ariane Guglielmi Ariza; Teixeira, Lais Helena; Bargieri, Daniel Youssef; Boscardin, Silvia Beatriz; Soares, Irene da Silva; Nussenzweig, Ruth Sonntag; Nussenzweig, Victor; Rodrigues, Mauricio Martins. "TLR5-dependent immunogenicity of a recombinant fusion protein containing an immunodominant epitope of malarial circumsporozoite protein and the FliC flagellin of Salmonella Typhimurium." Memorias do Instituto Oswaldo Cruz. 2011 Aug;106 Suppl 1:167-171
Mishra, Satish; Rai, Urvashi; Shiratsuchi, Takayuki; Li, Xiangming; Vanloubbeeck, Yannick; Cohen, Joe; Nussenzweig, Ruth S; Winzeler, Elizabeth A; Tsuji, Moriya; Nussenzweig, Victor. "Identification of non-CSP antigens bearing CD8 epitopes in mice immunized with irradiated sporozoites." Vaccine. 2011 Oct 6;29(43):7335-7342
Awards
- (Abraham Horwitz Award, 1985
- Paul Ehrlich and Ludwig Darmstaedter Prize, 1985
- Carlos J. Finlay Prize for Microbiology (Cuba) 1985
- Albert B. Sabin Gold Medal, 2008
- Warren Alpert Foundation Prize, 2015
- National Order of Scientific Merit (Brazil)
References
- ↑ NYU faculty page
- ↑ Nussenzweig, Ruth; J. Vanderberg; H. Most; C. Orton (14 October 1967). "Protective Immunity produced by the Injection of X-irradiated Sporozoites of Plasmodium berghei". Nature 216 (5111): 160–162. doi:10.1038/216160a0. PMID 6057225. Retrieved 2016-03-03.