S100
S100 or S-100 can refer to:
- S-100 bus, a type of computer bus
- S100 protein, a family of cellular antigens proteins
- Hondata s100, an engine tuning system for Honda and Acura cars
- QTEK S100, a re-badged HTC Magician Pocket PC phone
- The AVE Class 100, or Series 100, is a high speed train used for AVE services by the RENFE, in Spain. It was the first high speed train put into service in Spain, in 1992.
- USATC S100 Class, a 1942 0-6-0 steam locomotive class
- S-100, a predecessor to the S-200 Angara/Vega/Dubna surface-to-air missile system
- Canon Digital IXUS S100, a digital camera
- Canon PowerShot S100, a digital camera
- Guild S-100, a solid-body electric guitar
- IHO s-100, a standard for hydrographic information
- Schiebel Camcopter S-100, an unmanned aerial vehicle.
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