S100A2

S100 calcium binding protein A2

Rendering based on PDB 2RGI.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols S100A2 ; CAN19; S100L
External IDs OMIM: 176993 HomoloGene: 48389 GeneCards: S100A2 Gene
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez 6273 n/a
Ensembl ENSG00000196754 n/a
UniProt P29034 n/a
RefSeq (mRNA) NM_005978 n/a
RefSeq (protein) NP_005969 n/a
Location (UCSC) Chr 1:
153.56 – 153.57 Mb
n/a
PubMed search n/a

S100 calcium-binding protein A2 (S100A2) is a protein that in humans is encoded by the S100A2 gene.[1]

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer.[2]

References

Further reading


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