SDF4

Stromal cell derived factor 4
Identifiers
Symbols	SDF4 ; Cab45; SDF-4
External IDs	OMIM: 614282 MGI: 108079 HomoloGene: 32121 GeneCards: SDF4 Gene
Gene ontology Molecular function • calcium ion binding • protein binding • identical protein binding Cellular component • cytoplasm • late endosome • Golgi apparatus • Golgi lumen • plasma membrane • membrane • bleb • extracellular exosome Biological process • UV protection • calcium ion-dependent exocytosis • cerebellum development • fat cell differentiation • response to ethanol • zymogen granule exocytosis Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	51150	20318
Ensembl	ENSG00000078808	ENSMUSG00000029076
UniProt	Q9BRK5	Q61112
RefSeq (mRNA)	NM_016176	NM_001302467
RefSeq (protein)	NP_057260	NP_001289396
Location (UCSC)	Chr 1: 1.22 – 1.23 Mb	Chr 4: 155.99 – 156.01 Mb
PubMed search

45 kDa calcium-binding protein is a protein that in humans is encoded by the SDF4 gene.^[1][2][3]

References

1. Koivu T, Laitinen S, Riento K, Olkkonen VM (Sep 1997). "Sequence of a human cDNA encoding Cab45, a Ca2+-binding protein with six EF-hand motifs". DNA Seq 7 (3-4): 217–20. doi:10.3109/10425179709034038. PMID 9254016.
2. Scherer PE, Lederkremer GZ, Williams S, Fogliano M, Baldini G, Lodish HF (May 1996). "Cab45, a novel (Ca2+)-binding protein localized to the Golgi lumen". J Cell Biol 133 (2): 257–68. doi:10.1083/jcb.133.2.257. PMC 2120788. PMID 8609160.
3. "Entrez Gene: SDF4 stromal cell derived factor 4".

Further reading

• Honoré B, Vorum H (2000). "The CREC family, a novel family of multiple EF-hand, low-affinity Ca(2+)-binding proteins localised to the secretory pathway of mammalian cells.". FEBS Lett. 466 (1): 11–8. doi:10.1016/S0014-5793(99)01780-9. PMID 10648803.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
• Lam PP, Hyvärinen K, Kauppi M, et al. (2007). "A cytosolic splice variant of Cab45 interacts with Munc18b and impacts on amylase secretion by pancreatic acini.". Mol. Biol. Cell 18 (7): 2473–80. doi:10.1091/mbc.E06-10-0950. PMC 1924827. PMID 17442889.