SENP3

SUMO1/sentrin/SMT3 specific peptidase 3
Identifiers
Symbols SENP3 ; SMT3IP1; SSP3; Ulp1
External IDs OMIM: 612844 MGI: 2158736 HomoloGene: 9236 GeneCards: SENP3 Gene
EC number 3.4.22.68
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez 26168 80886
Ensembl ENSG00000161956 ENSMUSG00000005204
UniProt Q9H4L4 Q9EP97
RefSeq (mRNA) NM_015670 NM_001163571
RefSeq (protein) NP_056485 NP_001157043
Location (UCSC) Chr 17:
7.56 – 7.57 Mb
Chr 11:
69.67 – 69.68 Mb
PubMed search

SUMO1/sentrin/SMT3 specific peptidase 3, also known as SENP3, is a protein which in humans is encoded by the SENP3 gene.[1][2]

SENP3 together with SENP5, belongs to the Ulp1 branch in yeast and localize to nucleolus through B23/NPM1. SENP3 is associated and regulated by B23/nucleophosmin/NPM1 and involved in the regulation of ribosome biogenesis. SENP3 may be regulated by Arf-Mdm2-p53 pathway.[3]

References

  1. Yeh ET, Gong L, Kamitani T (May 2000). "Ubiquitin-like proteins: new wines in new bottles". Gene 248 (1–2): 1–14. doi:10.1016/S0378-1119(00)00139-6. PMID 10806345.
  2. Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (March 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  3. "Entrez Gene: SENP3 SUMO1/sentrin/SMT3 specific peptidase 3".


Further reading

This article is issued from Wikipedia - version of the Wednesday, September 02, 2015. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.