SEZ6

Seizure related 6 homolog (mouse)
Identifiers
Symbol	SEZ6
External IDs	MGI: 104745 HomoloGene: 10948 GeneCards: SEZ6 Gene
Gene ontology Cellular component • extracellular space • endoplasmic reticulum • plasma membrane • integral component of membrane • neuronal cell body • dendritic spine • dendritic shaft • perinuclear region of cytoplasm • apical dendrite Biological process • adult locomotory behavior • cerebellar Purkinje cell layer development • synapse maturation • excitatory postsynaptic potential • regulation of protein kinase C signaling • positive regulation of dendrite development • negative regulation of dendrite development Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	124925	20370
Ensembl	ENSG00000063015	ENSMUSG00000000632
UniProt	Q53EL9	Q7TSK2
RefSeq (mRNA)	NM_001098635	NM_001291225
RefSeq (protein)	NP_001092105	NP_001278154
Location (UCSC)	Chr 17: 28.95 – 29.01 Mb	Chr 11: 77.93 – 77.98 Mb
PubMed search

Seizure protein 6 homolog is a protein that in humans is encoded by the SEZ6 gene.^[1][2]

References

1. Yu ZL, Jiang JM, Wu DH, Xie HJ, Jiang JJ, Zhou L, Peng L, Bao GS (Dec 2006). "Febrile seizures are associated with mutation of seizure-related (SEZ) 6, a brain-specific gene". J Neurosci Res 85 (1): 166–72. doi:10.1002/jnr.21103. PMID 17086543.
2. "Entrez Gene: SEZ6 seizure related 6 homolog (mouse)".

Further reading

• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Kim MH, Gunnersen JM, Tan SS (2003). "Localized expression of the seizure-related gene SEZ-6 in developing and adult forebrains". Mech. Dev. 118 (1–2): 171–4. doi:10.1016/S0925-4773(02)00238-1. PMID 12351182.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Shimizu-Nishikawa K, Kajiwara K, Sugaya E (1995). "Cloning and characterization of seizure-related gene, SEZ-6". Biochem. Biophys. Res. Commun. 216 (1): 382–9. doi:10.1006/bbrc.1995.2635. PMID 7488116.