SFSWAP

Splicing factor, suppressor of white-apricot family

Available structures

Ortholog search: PDBe, RCSB

List of PDB id codes
2E5Z, 2E60

Identifiers

Symbols

SFSWAP ; SFRS8; SWAP

External IDs

OMIM: 601945 HomoloGene: 134548 GeneCards: SFSWAP Gene

Gene ontology
Molecular function	• RNA binding
Cellular component	• nucleus
Biological process	• transcription, DNA-templated • regulation of transcription, DNA-templated • mRNA splice site selection • mRNA processing • negative regulation of mRNA splicing, via spliceosome
Sources: Amigo / QuickGO

Orthologs

Species

Human

Mouse

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 12:
131.71 – 131.8 Mb

Chr 5:
129.5 – 129.57 Mb

PubMed search

Splicing factor, suppressor of white-apricot homolog is a protein in humans that is encoded by the SFSWAP gene.^[1]

This gene encodes a human homolog of Drosophila splicing regulatory protein. This gene autoregulates its expression by control of splicing of its first two introns. In addition, it also regulates the splicing of fibronectin and CD45 genes. Two transcript variants encoding different isoforms have been identified.^[1]

References

1 2 "Entrez Gene: Splicing factor, suppressor of white-apricot homolog (Drosophila)". Retrieved 2013-05-08.

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