SH3GLB2
| SH3-domain GRB2-like endophilin B2 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbols | SH3GLB2 ; PP6569; PP9455; RRIG1 | ||||||||||||
| External IDs | OMIM: 609288 MGI: 2385131 HomoloGene: 10595 GeneCards: SH3GLB2 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 56904 | 227700 | |||||||||||
| Ensembl | ENSG00000148341 | ENSMUSG00000026860 | |||||||||||
| UniProt | Q9NR46 | Q8R3V5 | |||||||||||
| RefSeq (mRNA) | NM_001287045 | NM_001289709 | |||||||||||
| RefSeq (protein) | NP_001273974 | NP_001276638 | |||||||||||
| Location (UCSC) |
Chr 9: 129.01 – 129.03 Mb |
Chr 2: 30.34 – 30.36 Mb | |||||||||||
| PubMed search | |||||||||||||
Endophilin-B2 is a protein that in humans is encoded by the SH3GLB2 gene.[1][2]
Interactions
SH3GLB2 has been shown to interact with SH3GLB1[1] and SH3KBP1.[3][4]
References
- 1 2 Pierrat B, Simonen M, Cueto M, Mestan J, Ferrigno P, Heim J (February 2001). "SH3GLB, a new endophilin-related protein family featuring an SH3 domain". Genomics 71 (2): 222–34. doi:10.1006/geno.2000.6378. PMID 11161816.
- ↑ "Entrez Gene: SH3GLB2 SH3-domain GRB2-like endophilin B2".
- ↑ Petrelli A, Gilestro GF, Lanzardo S, Comoglio PM, Migone N, Giordano S (March 2002). "The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met". Nature 416 (6877): 187–90. doi:10.1038/416187a. PMID 11894096.
- ↑ Soubeyran P, Kowanetz K, Szymkiewicz I, Langdon WY, Dikic I (March 2002). "Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors". Nature 416 (6877): 183–7. doi:10.1038/416183a. PMID 11894095.
Further reading
- Nagase T, Nakayama M, Nakajima D, Kikuno R, Ohara O (2001). "Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 8 (2): 85–95. doi:10.1093/dnares/8.2.85. PMID 11347906.
- Li J, Hawkins IC, Harvey CD, Jennings JL, Link AJ, Patton JG (2003). "Regulation of alternative splicing by SRrp86 and its interacting proteins.". Mol. Cell. Biol. 23 (21): 7437–47. doi:10.1128/MCB.23.21.7437-7447.2003. PMC 207616. PMID 14559993.
- Wan D, Gong Y, Qin W, Zhang P, Li J, Wei L, Zhou X, Li H, Qiu X, Zhong F, He L, Yu J, Yao G, Jiang H, Qian L, Yu Y, Shu H, Chen X, Xu H, Guo M, Pan Z, Chen Y, Ge C, Yang S, Gu J (2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression.". Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15724–9. doi:10.1073/pnas.0404089101. PMC 524842. PMID 15498874.
- Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
- Mikula M, Dzwonek A, Karczmarski J, Rubel T, Dadlez M, Wyrwicz LS, Bomsztyk K, Ostrowski J (2006). "Landscape of the hnRNP K protein-protein interactome.". Proteomics 6 (8): 2395–406. doi:10.1002/pmic.200500632. PMID 16518874.
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