SLC16A5

Solute carrier family 16 (monocarboxylate transporter), member 5
Identifiers
Symbols	SLC16A5 ; MCT5; MCT6
External IDs	OMIM: 603879 HomoloGene: 20985 IUPHAR: 995 GeneCards: SLC16A5 Gene
Gene ontology Molecular function • monocarboxylic acid transmembrane transporter activity • lactate transmembrane transporter activity • symporter activity • secondary active monocarboxylate transmembrane transporter activity Cellular component • integral component of plasma membrane • membrane Biological process • monocarboxylic acid transport • plasma membrane lactate transport Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	9121	217316
Ensembl	ENSG00000170190	ENSMUSG00000045775
UniProt	O15375	G5E8K6
RefSeq (mRNA)	NM_001271765	NM_001080934
RefSeq (protein)	NP_001258694	NP_001074403
Location (UCSC)	Chr 17: 75.09 – 75.11 Mb	Chr 11: 115.46 – 115.47 Mb
PubMed search

Solute carrier family 16, member 5 (monocarboxylic acid transporter 6) is a protein in humans that is encoded by the SLC16A5 gene. ^[1]

This gene encodes a member of the monocarboxylate transporter family and the major facilitator superfamily. The encoded protein is localized to the cell membrane and acts as a proton-linked transporter of bumetanide. Transport by the encoded protein is inhibited by four loop diuretics, nateglinide, thiazides, probenecid, and glibenclamide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012].

References

1. "Entrez Gene: Solute carrier family 16, member 5 (monocarboxylic acid transporter 6)". Retrieved 2013-06-27.

Further reading