SLC27A6

Solute carrier family 27 (fatty acid transporter), member 6
Identifiers
Symbols	SLC27A6 ; ACSVL2; FACVL2; FATP6; VLCS-H1
External IDs	OMIM: 604196 MGI: 3036230 HomoloGene: 38385 GeneCards: SLC27A6 Gene
Gene ontology Molecular function • nucleotide binding • long-chain fatty acid-CoA ligase activity • very long-chain fatty acid-CoA ligase activity Cellular component • plasma membrane • integral component of membrane • sarcolemma Biological process • very long-chain fatty acid metabolic process • long-chain fatty acid metabolic process • long-chain fatty acid transport • transmembrane transport Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	28965	225579
Ensembl	ENSG00000113396	ENSMUSG00000024600
UniProt	Q9Y2P4	E9Q9W4
RefSeq (mRNA)	NM_001017372	NM_001081072
RefSeq (protein)	NP_001017372	NP_001074541
Location (UCSC)	Chr 5: 128.54 – 129.03 Mb	Chr 18: 58.56 – 58.61 Mb
PubMed search

Long-chain fatty acid transport protein 6 is a protein that in humans is encoded by the SLC27A6 gene.^[1][2][3]

This gene encodes a member of the fatty acid transport protein family (FATP). FATPs are involved in the uptake of long-chain fatty acids and have unique expression patterns. Alternatively spliced transcript variants encoding the same protein have been found for this gene.^[3]

See also

• Solute carrier family

References

1. Gimeno RE, Ortegon AM, Patel S, Punreddy S, Ge P, Sun Y, Lodish HF, Stahl A (Apr 2003). "Characterization of a heart-specific fatty acid transport protein". J Biol Chem 278 (18): 16039–44. doi:10.1074/jbc.M211412200. PMID 12556534.
2. Steinberg SJ, Wang SJ, McGuinness MC, Watkins PA (Oct 1999). "Human liver-specific very-long-chain acyl-coenzyme A synthetase: cDNA cloning and characterization of a second enzymatically active protein". Mol Genet Metab 68 (1): 32–42. doi:10.1006/mgme.1999.2883. PMID 10479480.
3. "Entrez Gene: SLC27A6 solute carrier family 27 (fatty acid transporter), member 6".

Further reading

• Stelzl U, Worm U, Lalowski M, et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome.". Cell 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. PMID 16169070.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Steinberg SJ, Mihalik SJ, Kim DG, et al. (2000). "The human liver-specific homolog of very long-chain acyl-CoA synthetase is cholate:CoA ligase.". J. Biol. Chem. 275 (21): 15605–8. doi:10.1074/jbc.C000015200. PMID 10749848.
• Watkins PA, Pevsner J, Steinberg SJ (2000). "Human very long-chain acyl-CoA synthetase and two human homologs: initial characterization and relationship to fatty acid transport protein.". Prostaglandins Leukot. Essent. Fatty Acids 60 (5-6): 323–8. doi:10.1016/S0952-3278(99)80007-6. PMID 10471116.
• Hirsch D, Stahl A, Lodish HF (1998). "A family of fatty acid transporters conserved from mycobacterium to man.". Proc. Natl. Acad. Sci. U.S.A. 95 (15): 8625–9. doi:10.1073/pnas.95.15.8625. PMC 21126. PMID 9671728.