SPRY3
| Sprouty RTK signaling antagonist 3 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbols | SPRY3 ; spry-3 | ||||||||||||
| External IDs | OMIM: 300531 MGI: 1345188 HomoloGene: 4265 GeneCards: SPRY3 Gene | ||||||||||||
| |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 10251 | 236576 | |||||||||||
| Ensembl | ENSG00000168939 | ENSMUSG00000061654 | |||||||||||
| UniProt | O43610 | Q3UUD2 | |||||||||||
| RefSeq (mRNA) | NM_001304990 | NM_001030293 | |||||||||||
| RefSeq (protein) | NP_001291919 | NP_001025464 | |||||||||||
| Location (UCSC) |
Chr X: 155.77 – 155.78 Mb |
Chr GL456233.1: 0.1 – 0.11 Mb | |||||||||||
| PubMed search | |||||||||||||
Protein sprouty homolog 3 is a protein that in humans is encoded by the SPRY3 gene.[1][2]
References
- ↑ Hacohen N, Kramer S, Sutherland D, Hiromi Y, Krasnow MA (Feb 1998). "sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways". Cell 92 (2): 253–63. doi:10.1016/S0092-8674(00)80919-8. PMID 9458049.
- ↑ "Entrez Gene: SPRY3 sprouty homolog 3 (Drosophila)".
Further reading
- Ciccodicola A, D'Esposito M, Esposito T, et al. (2000). "Differentially regulated and evolved genes in the fully sequenced Xq/Yq pseudoautosomal region.". Hum. Mol. Genet. 9 (3): 395–401. doi:10.1093/hmg/9.3.395. PMID 10655549.
- Lim J, Wong ES, Ong SH, et al. (2000). "Sprouty proteins are targeted to membrane ruffles upon growth factor receptor tyrosine kinase activation. Identification of a novel translocation domain.". J. Biol. Chem. 275 (42): 32837–45. doi:10.1074/jbc.M002156200. PMID 10887178.
- Lim J, Yusoff P, Wong ES, et al. (2002). "The cysteine-rich sprouty translocation domain targets mitogen-activated protein kinase inhibitory proteins to phosphatidylinositol 4,5-bisphosphate in plasma membranes.". Mol. Cell. Biol. 22 (22): 7953–66. doi:10.1128/MCB.22.22.7953-7966.2002. PMC 134720. PMID 12391162.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Anteby EY, Natanson-Yaron S, Greenfield C, et al. (2005). "Human placental Hofbauer cells express sprouty proteins: a possible modulating mechanism of villous branching.". Placenta 26 (6): 476–83. doi:10.1016/j.placenta.2004.08.008. PMID 15950061.
- De Bonis ML, Cerase A, Matarazzo MR, et al. (2006). "Maintenance of X- and Y-inactivation of the pseudoautosomal (PAR2) gene SPRY3 is independent from DNA methylation and associated to multiple layers of epigenetic modifications.". Hum. Mol. Genet. 15 (7): 1123–32. doi:10.1093/hmg/ddl027. PMID 16500999.
- Cabrita MA, Jäggi F, Widjaja SP, Christofori G (2006). "A functional interaction between sprouty proteins and caveolin-1.". J. Biol. Chem. 281 (39): 29201–2912. doi:10.1074/jbc.M603921200. PMID 16877379.
External links
- SPRY3 human gene location in the UCSC Genome Browser.
- SPRY3 human gene details in the UCSC Genome Browser.
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