STX17

Syntaxin 17
Identifiers
Symbol	STX17
External IDs	OMIM: 604204 HomoloGene: 9917 GeneCards: STX17 Gene
Gene ontology Molecular function • SNARE binding • SNAP receptor activity • protein kinase binding • protein phosphatase binding Cellular component • autophagic vacuole membrane • mitochondrion • mitochondrion • lysosomal membrane • endoplasmic reticulum membrane • rough endoplasmic reticulum • endoplasmic reticulum-Golgi intermediate compartment • cytosol • ER to Golgi transport vesicle membrane • integral component of membrane • ER to Golgi transport vesicle • smooth endoplasmic reticulum membrane • SNARE complex • endoplasmic reticulum-Golgi intermediate compartment membrane • ER-mitochondrion membrane contact site Biological process • autophagic vacuole fusion • intracellular protein transport • ER to Golgi vesicle-mediated transport • vesicle fusion • Golgi organization • protein localization to pre-autophagosomal structure • vesicle docking • endoplasmic reticulum-Golgi intermediate compartment organization Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	55014	67727
Ensembl	ENSG00000136874	ENSMUSG00000061455
UniProt	P56962	Q9D0I4
RefSeq (mRNA)	NM_017919	NM_026343
RefSeq (protein)	NP_060389	NP_080619
Location (UCSC)	Chr 9: 99.91 – 99.97 Mb	Chr 4: 48.12 – 48.19 Mb
PubMed search

Syntaxin 17 is a protein that in humans is encoded by the STX17 gene.^[1]

References

1. "Entrez Gene: Syntaxin 17".

Further reading

• Itakura E, Kishi-Itakura C, Mizushima N (2012). "The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes". Cell 151 (6): 1256–69. doi:10.1016/j.cell.2012.11.001. PMID 23217709.
• Petukhova L, Duvic M, Hordinsky M, Norris D, Price V, Shimomura Y, Kim H, Singh P, Lee A, Chen WV, Meyer KC, Paus R, Jahoda CA, Amos CI, Gregersen PK, Christiano AM (2010). "Genome-wide association study in alopecia areata implicates both innate and adaptive immunity". Nature 466 (7302): 113–7. doi:10.1038/nature09114. PMC 2921172. PMID 20596022.
• Muppirala M, Gupta V, Swarup G (2011). "Syntaxin 17 cycles between the ER and ERGIC and is required to maintain the architecture of ERGIC and Golgi". Biol. Cell 103 (7): 333–50. doi:10.1042/BC20110006. PMID 21545355.
• Zhao ZZ, Duffy DL, Thomas SA, Martin NG, Hayward NK, Montgomery GW (2009). "Polymorphisms in the syntaxin 17 gene are not associated with human cutaneous malignant melanoma". Melanoma Res. 19 (2): 80–6. doi:10.1097/CMR.0b013e328322fc45. PMC 3665505. PMID 19209086.
• Steegmaier M, Yang B, Yoo JS, Huang B, Shen M, Yu S, Luo Y, Scheller RH (1998). "Three novel proteins of the syntaxin/SNAP-25 family". J. Biol. Chem. 273 (51): 34171–9. doi:10.1074/jbc.273.51.34171. PMID 9852078.
• Hay JC, Chao DS, Kuo CS, Scheller RH (1997). "Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells". Cell 89 (1): 149–58. doi:10.1016/s0092-8674(00)80191-9. PMID 9094723.
• Steegmaier M, Oorschot V, Klumperman J, Scheller RH (2000). "Syntaxin 17 is abundant in steroidogenic cells and implicated in smooth endoplasmic reticulum membrane dynamics". Mol. Biol. Cell 11 (8): 2719–31. doi:10.1091/mbc.11.8.2719. PMC 14951. PMID 10930465.